Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo2469Conserved hypothetical protein. Homology to bb1298 of B. brochiseptica of 64% (trembl|Q7WMU2). Pfam: Glyoxalase/Bleomycin restiant protein. no signal peptide. no TMHs. (138 aa)    
Predicted Functional Partners:
azo2673
Hypothetical protein,69% Identity (75% similarity) to TrEMBl;Q8XS84 Has PF06983, 3-demethylubiquinone-9 3-methyltransferase;IPR009725 3-dmu-93-mtfrase;This family represents a conserved region approximately 100 residues long within a number of bacterial and archaeal 3-demethylubiquinone-9 3-methyltransferases (EC:2.1.1.64). Note that some family members contain more than one copy of this region, and that many members are hypothetical proteins; Function unclear.
 
     0.641
lldD
Conserved hypothetical L-lactate dehydrogenase (cytochrome). Homology to lldD of B. bronchisptica of 51% (tremble:Q7WND1). InterPro: FMN-dependent alpha-hydroxy acid dehydrogenases (IPR000262); Protein binding FMN and related compounds core region (IPR003009). Pfam: FMN-dependent dehydrognease. no signal peptide. no TMHs; Family membership.
       0.522
trpA
TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
  0.500
trpB
TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.457
panE1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.452
azo2654
Lactoylglutathione lyase; Glyoxalase family protein, 54% identity (67% similarity) to TrEMBL;Q88HB6. Has PF00903,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;IPR004360, Gly_bleo_diox: Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric. The sequence of glyoxalase I is well conserved. This domain is found in other related proteins including the Bleomycin resistance protein and dioxygenases eg. 4-hydroxyp [...]
 
     0.445
azo2784
Conserved hypothetical monoamine oxidase. Homology to rsp0431 of R. solanacearum of 34% (trembl|Q8XSN6). In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. InterPro: Amine oxidase (IPR002937). Pfam: Flavin containing amine oxidase. probable signal peptide. no TMH; Family membership.
     
  0.427
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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