Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
azo2489Putative transport protein; Integral membrane proteins that mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions(sodium symporters). Hypothetical E.coli protein yfbS. Similar to TrkA. The NAD+ -binding protein TrkA is a component of a low-affinity K+ uptake system in Escherichia coli. This protein has the TrkA-C and TrkA-N domains. dass: anion transporter; High confidence in function and specificity. (614 aa)    
Predicted Functional Partners:
fumB
Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.582
txn
Thioredoxin-disulfide reductase; Putative Thioredoxin. Homology to txn (THIO_ICTPU) of I. punctatus of 36%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. InterPro: Thioredoxin (IPR0006662) Tigrfam: dsbE: periplasmic protein thiol:disulfie Oxidoreductase, DSB subfamily Pfam: Thioredoxin no signal peptide no TMHs; Family membership.
       0.551
sulP1
Putative sulfate transporter; Sulfate permease, SulP. Permease member of the MFS superfamily, involved in the transport of sulfate. Putative sulfate transporter ychM. InterPro: IPR002645; STAS. IPR001902; Sulph_transpt. Pfam: PF01740; STAS; 1. PF00916; Sulfate_transp; 1. SignalP: present. HIGH-AFFINITY H+/SULFATE COTRANSPORTER THAT MEDIATES THE UPTAKE OF SULFATE BY PLANT ROOTS FROM LOW CONCENTRATIONS OF SULFATE IN THE SOIL SOLUTION; High confidence in function and specificity.
 
 
 0.481
maeB1
Probable malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) (EC 1.1.1.40) (NADP-ME). Homology to dme of S. meliloti of 60% (sprot|MAO1_RHIME). Required for symbiotic nitrogen fixation. Plays a key role in the conversion of malate to acetyl-CoA for efficient tricarboxylic acid cycle function in nitrogen-fixating bacteria. Tigrfam: pta: phosphotransacetylase Pfam: Malic enzyme; Phosphate acetyl/butaryltransferase no signal peptide no TMHs; High confidence in function and specificity.
  
  
 0.476
maeB2
Probable malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+). Homology to dme of S. meliloti of 61% (sprot|MAO1_RHIME). Required for symbiotic nitrogen fixation. Plays a key role in the conversion of malate to acetyl-CoA for efficient tricarboxylic acid cycle function in nitrogen-fixating bacteria. InterPro: Phosphate acetyl/butaryl transferase (IPR002505); Malic enzyme (IPR001891) Pfam: Malic enzyme; Phosphate acetyl/butaryl transferase Tigrfam: pta: phosphotransacetylase no signal peptide no TMHs; High confidence in function and specificity.
  
  
 0.476
azo2488
Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs.
       0.465
sulP2
Putative sulfate transporter; Sulfate permease, SulP. Permease member of the MFS superfamily, involved in the transport of sulfate. Putative sulfate transporter ychM. InterPro: IPR002645; STAS. IPR001902; Sulph_transpt. Pfam: PF01740; STAS; 1. PF00916; Sulfate_transp; 1. SignalP: present; High confidence in function and specificity.
 
 
 0.458
cobA2
Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity; Belongs to the precorrin methyltransferase family.
     
 0.401
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (18%) [HD]