Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
azo2493Conserved hypothetical protein; Entry name:- TREMBL:Q8XXS1 InterPro IPR002539; MaoC_dehydratas. Pfam PF01575; MaoC_dehydratas; 1. Identities = 74/154 (48%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0. (177 aa)    
Predicted Functional Partners:
azo3042
NADPH quinone oxidoreductase, putative; ZP_00167050: 52% identity; 70% similarity. Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta- crystallin). DOES NOT HAVE ALCOHOL DEHYDROGENASE ACTIVITY. BINDS NADP AND ACTS THROUGH A ONE-ELECTRON TRANSFER PROCESS. ORTHOQUINONES ARE THE BEST SUBSTRATES. MAY ACT IN THE DETOXIFICATION OF XENOBIOTICS (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily InterPro:IPR002085; Adh_zn_family. Pfam:PF00107; ADH_zinc_N TIGRFAM: 2A0302: arginine/ornithine antiporter tdh: L-threonine 3-dehydrogenase; Function unclear.
 0.913
aidB2
Putative acyl-CoA dehydrogenase; The aidB gene encodes a protein of ca. 60 kDa that is homologous to several mammalian acyl coenzyme A dehydrogenases. Reaction:- acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor Entry name SWISSPROT:AIDB_ECOLI InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Identities = 85/289 (29%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership.
 
 0.896
azo1987
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Specificity unclear.
  
 0.851
fadB1
Probable enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Alpha-subunit of fatty acid oxidation complex. Entry name TREMBL:Q8G968 Prim. accession # Q8G968 Identities = 373/642 (58%) InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0 IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1; Family membership.
  
 0.732
fadB2
Short-chain enoyl-CoA hydratase activity. Activity:- 3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name TREMBL:Q8P986 Prim. accession # Q8P986 InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. IPR000205; NAD_BS. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1. Identities = 468/796 (58%) Prediction: Signal peptide Signal peptide probability: 0.980 Number of predicted TMHs: 0; Family membership.
  
 0.732
azo3768
Putative catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 0.703
fabD
Probable malonyl CoA-acyl carrier protein transacylase. Homology to fabD of E. coli of 54% (sprot|FABD_ECOLI). Is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein. InterPro: Acyl transferase domain (IPR001227); Manyl CoA-acyl carrier protein transaylase (IPR004410) Pfam: Acyl transferase domain Tigrfam: fabD: malonyl CoA-acyl carrier protein no signal peptide no TMHs; High confidence in function and specificity.
     
 0.702
etfA3
Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 65% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity.
  
 
 0.695
etfB3
Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein beta-subunit (IPR000049) Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity.
  
   0.666
norM
Multidrug resistance protein; The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae,and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. Functions as a Na(+)/drug antiporter. These proteins have 12 probable TMS,TREMBL:Q7NXN3 (35% identity); SWISSPROT:Q9K015 (32% identity). Pfam (UPF0013): Uncharacterized membrane protein family. TIGRFAM (TIGR00797): matE. TMHMM reporting 11 transmembrane helice [...]
  
 
  0.653
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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