Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fcbC1Probable thiesterase; 4-hydroxybenzoyl-CoA thioesterase (EC 3.1.2.23). This family contains a wide variety of enzymes,principally thioesterases. This family includes 4HBT which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3 InterPro:IPR008272; 4HBcoA_thiost_AS. IPR006683; Thioestr_supf. Pfam:PF03061; 4HBT InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site No signal peptide No transmembrane helices TIGR00051: conserved hypothetical protein; High confidence in function and specificity. (139 aa)    
Predicted Functional Partners:
fadD2
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain acyl-CoA synthetase). Esterification concomitant with transport of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q89CF2 (46% identity); TREMBL:Q89CJ5 (44% identity). Pfam (PF00501): AMP-binding enzyme; Specificity unclear.
 
  
 0.780
azo2496
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Specificity unclear.
    
  0.758
azo3056
Probable enoyl-coa-hydratase/isomerase; Activity:- (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name :- TREMBL:Q84HH6 InterPro :-IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Number of predicted TMHs: 0 Identities = 452/553 (81%); Family membership.
  
 
  0.744
nagI
Gentisate 1,2-dioxygenase; Involved in catabolism of naphthalene via gentisate to fumarate and pyruvate. NagI is a gentisate 1,2-dioxygenase which converts gentisate to maleylpyruvate. Similar to TREMBL:O86041 (66% identity); TREMBL:Q8X655 (30% identity); TREMBL:Q8Y0F7 (33% identity); High confidence in function and specificity.
 
     0.674
boxB
Benzoyl-CoA oxygenase component B. 85%; Function unclear.
  
     0.667
paaG3
Putative enoyl-CoA hydratase; Entry name SWISSPROT:PAAG_ECOLI InterPro :-IPR001753; EnCoA_hydrtse. Identities = 62/250 (24%) Pfam:-PF00378; ECH; 1. function:-Could possibly oxidizes fatty acids using specific components (by similarity). catalytic activity :-(3s)-3-hydroxyacyl-coa = trans-2(or 3)-enoyl-coa + h(2)o. Number of predicted TMHs: 0; Family membership; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
  0.644
acpP
AcpP protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.598
azo0259
Conserved hypothetical protein. Homology to xac 4098 of X. axonapodis of 36% (trembl|Q8PF87). No domains predicted. No signal peptide. No TMHs.
    
 0.588
azo0260
Conserved hypothetical protein; Entry name:- TREMBL:Q87EI7 InterPro:- IPR000873; AMP-bind. Pfam:- PF00501; AMP-binding; 2. Identity :- 45% Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0.
    
 0.588
fadB1
Probable enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Alpha-subunit of fatty acid oxidation complex. Entry name TREMBL:Q8G968 Prim. accession # Q8G968 Identities = 373/642 (58%) InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0 IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1; Family membership.
  
 
 0.587
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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