STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fadD2Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain acyl-CoA synthetase). Esterification concomitant with transport of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q89CF2 (46% identity); TREMBL:Q89CJ5 (44% identity). Pfam (PF00501): AMP-binding enzyme; Specificity unclear. (622 aa)    
Predicted Functional Partners:
paaG3
Putative enoyl-CoA hydratase; Entry name SWISSPROT:PAAG_ECOLI InterPro :-IPR001753; EnCoA_hydrtse. Identities = 62/250 (24%) Pfam:-PF00378; ECH; 1. function:-Could possibly oxidizes fatty acids using specific components (by similarity). catalytic activity :-(3s)-3-hydroxyacyl-coa = trans-2(or 3)-enoyl-coa + h(2)o. Number of predicted TMHs: 0; Family membership; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.881
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.828
acpP
AcpP protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.814
azo0262
Hypothetical protein; Similar to TREMBL:Q9PFA7 (61% identity); TREMBL:Q87AD9 (61% identity); SWISSPROT:Q7VKH6 (34% identity); Function unclear; ORF1.
  
 0.808
azo0285
Conserved hypothetical acyl carrier protein. Homology to psptO5093 of P. syringae of 44% (trembl|Q87V48). Interpro: Phosphopanteteine-binding (IPR00613). Pfam: Phosphopantetheine attachment site (PF00550) Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. Tigrfam: acyl_carrier: acyl carrier protein. no signal peptide. no TMHs; Conserved hypothetical protein.
  
 0.808
azo3252
Conserved hypothetical protein. Homology to ne2163 of N. europaea of 42% (trembl|Q82SY3). Pfam: Poshpopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. no signal peptide. no TMHS.
  
 0.808
azo3042
NADPH quinone oxidoreductase, putative; ZP_00167050: 52% identity; 70% similarity. Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta- crystallin). DOES NOT HAVE ALCOHOL DEHYDROGENASE ACTIVITY. BINDS NADP AND ACTS THROUGH A ONE-ELECTRON TRANSFER PROCESS. ORTHOQUINONES ARE THE BEST SUBSTRATES. MAY ACT IN THE DETOXIFICATION OF XENOBIOTICS (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily InterPro:IPR002085; Adh_zn_family. Pfam:PF00107; ADH_zinc_N TIGRFAM: 2A0302: arginine/ornithine antiporter tdh: L-threonine 3-dehydrogenase; Function unclear.
 
 
 0.781
fcbC1
Probable thiesterase; 4-hydroxybenzoyl-CoA thioesterase (EC 3.1.2.23). This family contains a wide variety of enzymes,principally thioesterases. This family includes 4HBT which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3 InterPro:IPR008272; 4HBcoA_thiost_AS. IPR006683; Thioestr_supf. Pfam:PF03061; 4HBT InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site No signal peptide No transmembrane helices TIGR00051: conserved hypothetical protein; High confidence in function and specificity.
 
  
 0.780
azo2279
Conserved hypothetical protein. Homology to Avin02000067 of Azotobacter vinelandii of 50% (gi|23105742|ref|ZP_00092196.1|(NBCI ENTREZ)). InterPro: Ankyrin-repeat. The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids.The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures [...]
    
 0.777
azo3595
Hypothetical protein predicted by Glimmer/Critica.
    
 0.777
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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