STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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azo2503ABC transporter permease protein; Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q7W5E8 (62%), to sprot|BRAD_PSEAE (25%) and to sprot|LIVH_ECOLI (26%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting nine Tmhe [...] (345 aa)    
Predicted Functional Partners:
azo2502
Probable branched-chain amino acid ABC transporter,ATP binding protein,; Specificity unclear; Belongs to the binding-protein-dependent transport system permease family.
 
 0.988
azo0313
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. The integral inner-membrane proteins translocate the substrate across the membrane. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX5 (54%) and to trembl|Q8UFI6 (47%). Pfam: ABC transporter Pfam (PF02653): Branched-chain amino acid transport system / permease component Smart : AAA ATPase SignalP reporting Signal pept [...]
 
 0.972
azo1992
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. The integral inner-membrane proteins translocate the substrate across the membrane. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX5 (52%) and to trembl|Q89CG4 (45%). Pfam (PF00005): ABC transporter Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) Smart (SM00382): AAA ATPase [...]
 
 0.972
azo2501
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX4 (66%) and to trembl|Q89PQ7 (62%). Smart: AAA ATPases; Specificity unclear.
 
 0.934
azo0311
ABC transporter substrate binding proteins count to the family of extracellular ligand binding proteins. It is a component of the high affinity amino acid transport system. Similar to trembl|Q8XU64 (71%) and to sprot|LIVJ_ECOLI (16%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide; Specificity unclear.
  
 
  0.867
braC
Putative Leu/Ile/Val-binding protein; The transport of branched-chain amino acids in P. aeruginosa is mediated by two distinct systems, the leucine, isoleucine, and valine I and II transports systems. Periplasmic binding proteins are found to participate in the transport of amino acids, sugars, and ions. BraC is the structural gene for periplasmic binding proteins in P. aeruginosa. Similar to trembl|Q9RYP6 (49%) and to sprot|BRAC_PSEAE (22%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide; Specificity unclear.
  
 
  0.867
livK2
Putative leucine-specific binding protein; In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar sprot|LIVK_ECOLI (21%) and to trembl|Q9RYP6 (50%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide; Specificity unclear.
  
 
  0.867
livG2
ABC transporter ATP-binding protein; Probable high-affinity branched-chain amino acid transport ATP-binding protein BraF. ATP-binding cassette (ABC) transporters are multidomain membrane proteins,responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. BraF is a COMPONENT OF THE HIGH AFFINITY LEUCINE ISOLEUCINE VALINE TRANSPORT SYSTEM (LIV-I) WHICH IS OPERATIVE WITHOUT NA(+) AND IS SPECIFIC FOR ALANINE AND THREONINE IN AD [...]
 
 0.865
livM5
Putative branched-chain amino acid transport permease. Homology to livM of S. typhimurium of 44%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. no signal peptide probable 8 TMHs; Specificity unclear.
 
 0.849
azo0314
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX4 (68%) and to trembl|Q7WCY5 (63%). Smart: AAA ATPases; Specificity unclear.
 
 0.848
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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