STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2512Probable FecR-like transmembrane sensor involved in iron metabolism. FecR is involved in regulation of iron dicitrate transport. In the absence of citrate FecR inactivates FecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm; High confidence in function and specificity. (338 aa)    
Predicted Functional Partners:
fpvA1
Iron-regulated outer membrane protein. TonB-dependent receptor protein. Homolog to fpvA, a ferripyoverdine receptor precursor in P. aeruginosa. Similar to PupA protein of P. putida WCS,this protein is a receptor for the iron-bound form of pesudobactin, a compound structurally very; High confidence in function and specificity.
 
 
 0.963
azo2513
Putative sigma factor, ECF subfamily; Probable fecI-like RNA polymerase sigma factor. THE SIGMA FACTOR IS AN INITIATION FACTOR THAT PROMOTES ATTACHMENT OF THE RNA POLYMERASE TO SPECIFIC INITIATION SITES AND THEN IS RELEASED. THIS SIGMA FACTOR REGULATES THE FEC GENES FOR IRON DICITRATE TRANSPORT (PROBABLE). InterPro: Sigma factor ECF subfamily; Specificity unclear.
 
 0.941
fpvA2
Iron-regulated outer membrane protein. TonB-dependent receptor protein. Homolog to fpvA, a ferripyoverdine receptor precursor in P. aeruginosa. Similar to PupA protein of P. putida WCS,this protein is a receptor for the iron-bound form of pesudobactin, a compound structurally very; High confidence in function and specificity.
 
 
 0.935
fecI
Putative sigma-70 factor, ECF subfamily; FecI: belongs to the extracytoplasmic-function (ECF) sigma factor, which represent a subgroup of the sigma 70 family. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Involved in iron metabolism; High confidence in function and specificity.
 
 0.874
fecA
Ferric-citrate outer membrane receptor,FecA.Involved in the recognition and internalization of ferric-citrate in E.coli. SPECIFIC RECEPTOR FOR THE SIDEROPHORE FERRIC PSEUDOBACTIN 358. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.
 
  
 0.723
fyuA
Putative TonB-dependent receptor; Yersinia enterocolitica,iron-repressible outer membrane protein, FyuA. FyuA:RECEPTOR FOR THE BACTERIOCIN PESTICIN AND FOR THE SIDEROPHORE YERSINIABACTIN. TonB-dependent outer membrane receptor; Function unclear.
 
  
 0.644
azo2996
Conserved hypothetical membrane protein. Homology to PA2403 of Pseudomonas aeruginosa of 38% (trembl|Q8G8F6). Has 3 copies of PF03929, PepSY-associated TM helix;IPR005625 pEPsy_tm; This domain represents a conserved TM helix found in bacterial proteins. Has PF03413, Peptidase propeptide and YPEB domain; IPR005075,Propep_PepSY:This region is likely to have an protease inhibitory function (personal obs:C Yeats). This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to no [...]
 
   
 0.614
azo0251
Conserved hypothetical membrane protein, 38% similarity to trEMBL;Q7WDT1,Putative membrane protein [BB4906] [Bordetella bronchiseptica (Alcaligenes bronchisepticus)]. TMHMM2 predicts 6 TMH's present. No signal peptide present; Family membership.
  
     0.563
fhuF
Putative TonB-dependent receptor; Ferrioxamine B receptor precursor, FhuF. Iron-regulated outer membrane protein that bind and uptake ferrioxamine in association with the TonB protein. Involved in the reduction of ferric iron in cytoplasmic ferrioxamine B. Binds 1 2Fe-2S cluster. In e.coli the fhuF gene reacts very sensitive to minor changes of Fe2+ and Fur(Ferric uptake regulator). SWISSPROT: FOXA_SALTY. Prim. accession #:Q56145 EMBL: AE008712; AAL19318.1; AF060876; AAC15464.1; U62282; AAB04552.1; InterPro:IPR000531; TonB_boxC. Pfam: PF00593; TonB_dep_Rec; 1. PROSITE: PS00430; TONB_DE [...]
 
  
 0.509
azo0230
Conserved hypothetical secreted protein. Homology to RPA1846 of R.palustris of 39% (trembl:Q6N8Q7). No domains predicted. No TMHs. Signal peptide present; Conserved hypothetical protein.
  
     0.504
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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