STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pobR2Transcriptional regulator, AraC family,; High confidence in function and specificity. (295 aa)    
Predicted Functional Partners:
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
    
  0.615
azo2527
Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450; Family membership.
 
     0.562
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.556
ligB2
Protocatechuate 4,5-dioxygenase beta chain subunit,having 91% similarity(85% identity)to TrEMBL;Q6N0Q9,Protocatechuate 3,4-dioxygenase beta chain [pcaH] [Xanthomonas axonopodis (pv. citri)]Swiss-Prot: P22636;PF02900;IPR004183; Catalytic LigB subunit of aromatic ring-opening dioxygenase.The LigAB enzyme (a protocatechuate 4,5-dioxygenase EC: 1.13.11.8), of Sphingomonas paucimobilis oxidizes protocatechuate (or 3,4-dihydroxybenzoic acid, PCA). The enzyme belongs to the class III extradiol-type catecholic dioxygenase family,which catalyzes the ring-opening reaction of protocatechuate and [...]
  
     0.554
ligA2
[EC:1.13.11.8], Protocatechuate 4,5-dioxygenase alpha chain (EC 1.13.11.8) (4,5-PCD)., Aromatic-ring-opening dioxygenase LigAB, LigA subunit; High confidence in function and specificity.
  
     0.553
ligB1
Protocatechuate 4,5-dioxygenase beta chain subunit,having 63% similarity(48% identity)to TrEMBL;Q8PP10,Protocatechuate 3,4-dioxygenase beta chain [pcaH] [Xanthomonas axonopodis (pv. citri)] Swiss-Prot: P22636 PF02900;IPR004183; Catalytic LigB subunit of aromatic ring-opening dioxygenase.The LigAB enzyme (a protocatechuate 4,5-dioxygenase EC: 1.13.11.8), of Sphingomonas paucimobilis oxidizes protocatechuate (or 3,4-dihydroxybenzoic acid, PCA). The enzyme belongs to the class III extradiol-type catecholic dioxygenase family,which catalyzes the ring-opening reaction of protocatechuate and [...]
  
     0.546
ligA1
Protocatechuate 4,5-dioxygenase alpha subunit, 39% Identity to TrEMBL;Q6N0R0,Q6NB24, Q9KWL5. Has PF07746Aromatic-ring-opening dioxygenase LigAB, LigA subunit; TMHMM2 reports 1 TMH.
  
     0.542
ligC
Hypothetical oxidoreductase yrbE (EC 1.-.-.-). TREMBL:Q93PS4:90% identity; 93% similarity. This group of enzymes utilise NADP or NAD, and is known as the GFO/IDH/MOCA family in Swiss-Prot. GFO is a glucose--fructose oxidoreductase, which converts D-glucose and D-fructose into D-gluconolactone and D-glucitol in the sorbitol-gluconate pathway. MOCA is a rhizopine catabolism protein which may catalyze the NADH-dependent dehydrogenase reaction involved in rhizopine catabolism. Other proteins belonging to this family include Gal80, a negative regulator for the expression of lactose and gala [...]
  
     0.523
ligI
Probable 2-pyrone-4,6-dicarboxylate hydrolase. Homology to ligI of S. paucimobilis of 55% (tremble:O87170) Pfam: Amidohydrolase no signal peptide no TMHs; High confidence in function and specificity.
  
     0.507
pobA
4-hydroxybenzoate 3-monooxygenase; P-hydroxybenzoate hydroxylase InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase); High confidence in function and specificity.
 
   
 0.485
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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