STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nacNitrogen assimilation regulatory protein nac (Nitrogen assimilation control protein). TRANSCRIPTIONAL ACTIVATOR FOR THE HUT PUT AND URE OPERONS AND REPRESSOR FOR THE GDH AND GLTB OPERONS IN RESPONSE TO NITROGEN LIMITATION. NEGATIVE REGULATOR OF ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|NAC_KLEAE (30% Klebsiella aerogenes, nitrogen assimilation regulatory protein nac (nitrogen assimilation control protein)) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Specificity unclear. (388 aa)    
Predicted Functional Partners:
yeaT
Putative transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
  
     0.664
bcr1
Bicyclomycin resistance protein homolog. Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase (By similarity). InterPro: General substrate transporters efflux_Bcr_CflA: drug resistance tran Also show similarity to bssH of bssDCABEFGH operon-genes involved in anaerobic degradation of toulene in denitryfing bacterium, Azoarcus strain EbN1; High confidence in function and specificity.
 
     0.636
azo1015
Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.595
azo0132
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.593
ligI
Probable 2-pyrone-4,6-dicarboxylate hydrolase. Homology to ligI of S. paucimobilis of 55% (tremble:O87170) Pfam: Amidohydrolase no signal peptide no TMHs; High confidence in function and specificity.
 
     0.586
fldW
4-oxalomesaconate hydratase These proteins are related to the metal-dependent hydrolase superfamily tremblnew|CAE30137: 86% identity, 93% similarity InterPro:IPR006992; Amidohydro_2. Pfam:PF04909; Amidohydro_2 Absence of traansmembrane helices (TMHMM predicted); High confidence in function and specificity.
 
     0.579
azo1925
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.538
azo2367
Transcriptional regulator, LysR family,; Function unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.520
azo2541
Acyl transferase, putative; Possible acyl transferase; Family membership.
 
     0.502
azo2360
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.482
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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