STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2556Hypothetical protein; No Good Homology with any hits in the DB. Conserved Hypothetical Protein,34% similarity to TrEMBL;Q8E9W3. Has PF03160:IPR003644:Calx_beta;Na-Ca exchanger/integrin-beta4:This domain has been found in Na-Ca exchangers and integrin subunit beta4, as well as some cyanobacterial proteins. Has 3 CA(Cadherin repeats)domains;SMART:SM00112;IPR002126:Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium. Has 1 CADG,Dystrogly [...] (1918 aa)    
Predicted Functional Partners:
azo2558
Membrane protein with HlyD domain; Family membership.
 
     0.880
azo2557
HlyD family secretion protein; Similar to MacA; Family membership.
 
     0.875
nodT
Putative outer membrane efflux protein. Homology to nodT from Rhizobium leguminosarum of 20% over 432 aa. The OEP family (Outer membrane efflux protein)allow export of a variety of substrates in Gram negative bacteria. Most members of NodT family are likely to export primarily small molecules rather than proteins. InterPro: Outer membrane efflux protein. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership.
 
     0.729
azo2555
HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
     0.681
azo0649
Conserved hypothetical protein. Homology to ebA1795 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebA1795(KEGG)). No domains predicted. No TMHs.
  
  
  0.544
azo2559
Conserved hypothetical secreted protein. Homology to Mflag03001539 of Methylobacillus flagellatus of 38% (gi|45521149|ref|ZP_00172671.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein.
       0.512
azo1264
Putative transmembrane sensor protein, no similarity to other bacterial proteins. Best hits to mus musculus and homo sapiens. Domains (LCCL_dom and TIR) are found in proteins (animal and plants) involved in protection against bacterial infection. InterPro: IPR004043 LCCL_dom. IPR000157 TIR. TMHMM reporting 1 transmembrane helices.
  
  
  0.436
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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