ATP-binding/permease fusion ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.

Membrane protein with HlyD domain; Family membership.

HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

Hypothetical protein; No Good Homology with any hits in the DB. Conserved Hypothetical Protein,34% similarity to TrEMBL;Q8E9W3. Has PF03160:IPR003644:Calx_beta;Na-Ca exchanger/integrin-beta4:This domain has been found in Na-Ca exchangers and integrin subunit beta4, as well as some cyanobacterial proteins. Has 3 CA(Cadherin repeats)domains;SMART:SM00112;IPR002126:Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium. Has 1 CADG,Dystrogly [...]

Putative outer membrane efflux protein. Homology to aggA from P. putida of 35%. The OEP family (outer membrane efflux protein) allow export of a variety of substrates in Gram negative bacteria. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHs; Function unclear.

Putative outer membrane effluxe protein protein. Homology to tolC from E. coli of 33%. The OEP family (outer membreane effluxe protein) allow export of a variety of substrates in Gram negative bacteria. TolC is believed to be a membre af an ABC transporter system for protein secretion without cleavage of a signal sequence. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership.

ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8DJ46 (29% identity); TREMBL:Q8YZK5 (29% identity). InterPro (IPR003838): Protein of unknown function DUF214. Pfam (DUF214): Predicted permease. TMHMM reporting four transmembrane helices. TC (3.A.1.122.): The Macr [...]

ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8YZK5 (28% identity); TREMBL:Q8DJ46 (29% identity). Pfam (DUF214): Predicted permease. TMHMM reporting five transmembrane helices. TC (3.A.1.122.): The Macrolide Exporter (MacB) Family; Specificity unclear.

RND efflux transporter, permease protein; AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q8KAV4 (43% identity); SWISSPROT:P25197 (23% identity). InterPro (IPR001036): Acriflavin resistance protein. PFam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TMHMM [...]