STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2565Conserved hypothetical membrane protein. Homology to BB1303 of Bordetella bronchiseptica of 50% (trembl|Q7WMT7). No domains predicted. TMHMM2 reporting 1 TMH present. No signal peptide present; Conserved hypothetical protein. (272 aa)    
Predicted Functional Partners:
azo2564
Putative RNA polymerase sigma factor,57% Identity to TrEMBL;Q7VV01, 49% Identity to TrEMBL;Q8XV48,53% to Q63LJ3. Has PF04542, Sigma-70 region 2; IPR007627,Sigma70_r2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit,beta prime. The aromatic residues of the recognition [...]
 
 
 0.976
azo2563
Conserved hypothetical secreted secreted protein. Homology to bb1301 of B. bronchiseptica of 59% (trembl|Q7WMT9). Pfam: Lipoprotein_15. This family occurs as tandem repeats in a set of lipoproteins. The alignment contains a Y-X4-D motif. signal peptide. no TMHs; Conserved hypothetical protein.
 
     0.948
rpoE
Probable RNA polymerase sigma-E factor (sigma-24),; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.768
sigW
Putative RNA polymerase sigma factor, Myxococcus xanthus carQ; Alcaligenes eutrophus plasmid pMOL28-encoded cnrH; Escherichia coli fecI; Pseudomonas syringae hrpL; rpoE from Escherichia coli, Salmonella typhimurium and Haemophilus influenzae; Streptomyces coelicolor sigE; and Bacillus subtilis sigma factors sigV, sigX, sigY and sigZ; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.768
algU
RNA polymerase sigma factor, Myxococcus xanthus carQ; Alcaligenes eutrophus plasmid pMOL28-encoded cnrH; Escherichia coli fecI; Pseudomonas syringae hrpL; rpoE from Escherichia coli, Salmonella typhimurium and Haemophilus influenzae; Streptomyces coelicolor sigE; and Bacillus subtilis sigma factors sigV, sigX, sigY and sigZ; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.768
fecI
Putative sigma-70 factor, ECF subfamily; FecI: belongs to the extracytoplasmic-function (ECF) sigma factor, which represent a subgroup of the sigma 70 family. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Involved in iron metabolism; High confidence in function and specificity.
  
 
 0.768
azo2513
Putative sigma factor, ECF subfamily; Probable fecI-like RNA polymerase sigma factor. THE SIGMA FACTOR IS AN INITIATION FACTOR THAT PROMOTES ATTACHMENT OF THE RNA POLYMERASE TO SPECIFIC INITIATION SITES AND THEN IS RELEASED. THIS SIGMA FACTOR REGULATES THE FEC GENES FOR IRON DICITRATE TRANSPORT (PROBABLE). InterPro: Sigma factor ECF subfamily; Specificity unclear.
  
 
 0.768
sigX
Putative RNA polymerase sigma factor, Myxococcus xanthus carQ; Alcaligenes eutrophus plasmid pMOL28-encoded cnrH; Escherichia coli fecI; Pseudomonas syringae hrpL; rpoE from Escherichia coli, Salmonella typhimurium and Haemophilus influenzae; Streptomyces coelicolor sigE; and Bacillus subtilis sigma factors sigV, sigX, sigY and sigZ; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.768
sigZ
Putative RNA polymerase sigma factor sigZ. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Similar to SWISSPROT: sprot|SIGZ_BACSU (23% Bacillus subtilis, RNA polymerase sigma factor SigZ) / sprot|RPSH_PSEAE (28% Pseudomonas aeruginosa, RNA polymerase sigma-h factor (sigma-30), AlgU or AlgT) InterPro: IPR000838 Sigma70_ECF. Pfam: PF07638 ECF sigma factor; High confidence in function and specificity.
  
 
 0.768
azo3153
Probable RNA polymerase sigma factor, 62% Identity to TrEMBL;Q8XXN5, Q7P0I2. Has PF04542, Sigma-70 region 2;IPR007627, Sigma70_r2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix,interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of th [...]
  
 
 0.768
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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