STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (363 aa)    
Predicted Functional Partners:
azo3494
Conserved hypothetical membrane protein. Homology to CV0155 of Chromobacterium violaceum of 69% (trembl|Q7P1Q8). Has PF03653, Uncharacterised protein family (UPF0093);IPR005265, Cons_hypoth701:It appears the conserved hypothetical integral membrane proteins of this family are found only in gram negative bacteria and their function is unknown. No signal peptide. 4 TMHs; Conserved hypothetical protein.
 
  
 0.962
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.939
coxD
Putative protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.929
cyaY
Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
    
 0.906
azo2583
Conserved hypothetical membrane protein. Homology to rs02279 of R. solanacearum of 53% (trembl|Q8Y388(SRS)). No domains predicted. No signal peptide. 4 TMHs; Conserved hypothetical protein.
       0.783
hrcA
Heat-inducible transcriptional repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
     
 0.774
bfr1
Putative bacterioferritin; Iron-storage protein.
     
 0.683
bfr2
Putative bacterioferritin; Iron-storage protein.
     
 0.683
hemF
HemF protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
   
 0.666
azo2630
Cobalamin biosynthesis protein, putative; CobN Magnesium Chelatase family protein, by similarity; Family membership.
     
 0.651
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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