Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ubiG3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (233 aa)    
Predicted Functional Partners:
ubiH
Probable 2-octaprenyl-6-methoxyphenol hydroxylase oxidoreductase protein; ubiH; aromatic-ring hydroxylase (flavoprotein monooxygenase) Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone. Ubiquinone biosynthesis pathway, by similarity; High confidence in function and specificity.
 
 
 0.988
azo0723
Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity.
 
 
 0.979
coq7
Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
  
 0.978
azo0373
Conserved hypothetical peptidase. Homology to Rsp0969 of R. solanacearum of 51% (trembl|Q8XR90). Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership.
    
 0.905
azo0374
Conserved hypothetical peptidase. Homology to cv4084 of C. violaceum of 64% (trembl|Q7NQQ39. Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership.
    
 0.891
azo0372
Conserved hypothetical protein; Entry name SWISSPROT:YHBT_ECOLI Prim. accession # P45474 InterPro IPR003033; SCP2. Pfam PF02036; SCP2; 1. Prediction: Non-secretory protein Signal peptide probability: 0.001 Number of predicted TMHs: 0 Identities = 46/107 (42%).
     
 0.890
ubiB
Probable ubiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
  
 
 
 0.843
pobA
4-hydroxybenzoate 3-monooxygenase; P-hydroxybenzoate hydroxylase InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase); High confidence in function and specificity.
   
 0.807
ubiA
4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
 0.805
abmA
2-amninobenzoyl-CoA monooxygenase/reductase (EC 1.14.13.40) Homology to abmA of A. evansii of 86% (trembl|Q93FB8(SRS). natural fusion protein of a monooxygenase and a reductase; contains flavin. Pfam: Monooxygnease; NADH:flavin oxidoreductase/NADH oxidorecutase. no signal peptide. no TMHs; High confidence in function and specificity.
   
 0.791
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (22%) [HD]