Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo2592Conserved hypothetical protein. Homology to Daro03002419 of Dechloromonas aromatica of 51% (gi|41723832|ref|ZP_00150722.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs. (305 aa)    
Predicted Functional Partners:
azo2591
Conserved hypothetical secreted protein. Homology to Daro03002418 of Dechloromonas aromatica of 58% (gi|53730135|ref|ZP_00150721.2|(NBCI ENTREZ)). No domains predicted. No TMHs. signal peptide present.
  
    0.773
azo2593
Conserved hypothetical secreted protein. Homology to Daro03002420 of Dechloromonas aromatica of 39% (gi|41723833|ref|ZP_00150723.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein.
       0.728
azo2594
Conserved hypothetical membrane protein. Homology to CV2219 of Chromobacterium violaceum of 36% (trembl|Q7NVX2(SRS)). no domains predicted. no signal peptide. 1 TMHs; Conserved hypothetical protein.
       0.720
azo2595
Conserved hypothetical secreted protein. Homology to Daro03002422 of Dechloromonas aromatica of 63% (gi|41723835|ref|ZP_00150725.1|(NBCI ENTREZ)). No domains predicted. No TMHs. signal peptide present; Conserved hypothetical protein.
       0.658
azo2596
Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs.
       0.597
azo2597
Hpyothetical protein with TIR domain. no homology to the data bank. Interpro: TIR domain Pfam: TIR doamin. Site directed mutagenesis and deletion analysis have shown that the TIR domain is essential for Toll and IL-1R activities. Sequence analysis have revealed the presence of three highly conserved regions among the different members of the family: box 1 (FDAFISY), box 2 (GYKLC-RD-PG), and box 3 (a conserved W surrounded by basic residues). It has been proposed that boxes 1 and 2 are involved in the binding of proteins involved in signaling,whereas box 3 is primarily involved in direc [...]
       0.574
mauA
Probable methylamine dehydrogenase. Homology to mauD of P. denifrificans of 45% (CAA67190) carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. InterPro: Methylamine dehydrogenase L subunit (IPR004229) Pfam: Methylamine dehydrogenase, L chain signal peptide no TMHs; High confidence in function and specificity.
   
   0.564
qhpB
Probable quinohemoprotein amine dehydrogenase,alpha subunit. Homology to qhpB of P.putida of 50% (gi|34809688|pdb|1PBY|B(PDB (RCSB))). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric e [...]
   
 
 0.450
maub
Methylamine dehydrogenase heavy chain precursor (MADH):- Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. Entry name SWISSPROT:DHMH_METEX Prim. accession # Q49124 Identities = 100/339 (29%) Prediction: Signal peptide Signal peptide probability: 1.000 Number of predicted TMHs: 0; Family membership.
   
 
 0.450
azo2935
Conserved hypothetical protein TMHMM2 reporting the presence of 1 TMH's. No Signal peptide present. Has 2 WD40 repeats;SMART;SM00320, Beta-transducin (G-beta) is one of the three subunits (alpha, beta, and gamma) of the guanine nucleotide-binding proteins (G proteins) which act as intermediaries in the transduction of signals generated by transmembrane receptors (see IPR001632). The alpha subunit binds to and hydrolyzes GTP; the functions of the beta and gamma subunits are less clear but they seem to be required for the replacement of GDP by GTP as well as for membrane anchoring and re [...]
   
 
 0.450
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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