STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2619Putative methyltransferase; Similar to TREMBL:Q98BY2 (39% identity); TREMBL:Q9A2R1 (40% identity); TREMBL:Q89KG6 (34% identity). Pfam (PF01209): ubiE/COQ5 methyltransferase family; Function unclear. (285 aa)    
Predicted Functional Partners:
soxR
Probable redox-sensitive transcriptional activator,; High confidence in function and specificity.
 
     0.764
azo2527
Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450; Family membership.
  
 
 0.702
azo2616
Lactoylglutathione lyase; Puatative Glyoxalase sub unit, 37% identitcal to TrEMBL;Q89MF5 Has PF00903, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;IPR004360, Gly_bleo_diox: Glyoxalase I, catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric. The sequence of glyoxalase I is well conserved. This domain is found in other related proteins including the Bleomycin resistance protein and dioxygenases eg. 4-hydroxyphenylpyruv [...]
 
     0.647
azo2615
Hypothetical protein,45% similarity to TrEMBL;Q6LHM7. No Good homology over entire length in the DB. No signal Peptide or TMH present; Function unclear.
 
 
  0.627
azo1825
Conserved hypothetical membrane protein. Homology to smb20339 of S. meliloti of 30% (trembl|Q92WL4(SRS)). No domains predicted. signal peptide. 1 TMH; Conserved hypothetical protein.
    
 0.592
azo2617
TREMBL:Q89L44: 48% identity.64% similarity. probable haloacid dehalogenase-like hydrolase. InterPro:IPR005834; Hydrolase. Pfam:PF00702; Hydrolase; Phosphoglycolate phosphatase(PGP). TIGR00099: conserved hypothetical prot; Function unclear.
   
   0.584
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.544
azo1783
Conserved hypothetical membrane protein. Homology to ebA6946 of Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebA6946(KEGG)). Pfam: Pospholipase D, active site motife; DedA family. no signal peptide. 6 TMHs; Conserved hypothetical protein.
  
 
  0.504
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.480
azo0032
Conserved hypothetical protein. Homology to nfa21510 of Nocardia farcinica of 31% (trembl:Q5YXU4). No domains predicted. No TMHs. No signal peptide.
  
     0.460
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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