STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2630Cobalamin biosynthesis protein, putative; CobN Magnesium Chelatase family protein, by similarity; Family membership. (1339 aa)    
Predicted Functional Partners:
azo2631
Conserved hypothetical membrane protein. Homology to NE0632 of Nitrosomonas europaea of 42% (trembl|Q82WN6(SRS)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein.
 
  
 0.965
azo2632
Conserved hypothetical membrane protein. Homology to PA1924 of P. aeruginosa of 43% (trembl|Q9I2I0(SRS)). No domains predicted. no signal peptide. probable 3TMHS; Conserved hypothetical protein.
 
  
 0.964
cobB
Cobyrinic acid AC-diamide synthase. Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine and one molecule of ATP is hydrogenolyzed for each amidation (By similarity). cbiA: cobyrinic acid ac-diamide synthase; High confidence in function and specificity.
 
 
 0.946
cbiE
Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); Precorrin-6 methyltransferase (Precorrin-6Y methylase). CATALYZES THE METHYLATION OF BOTH C-5 AND C-15 IN PRECORRIN-6Y TO FORM PRECORRIN-8X. InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity.
 
  
 0.900
cobO
Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
  
 0.794
azo3529
Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yiel [...]
 
  
 0.742
azo2860
Conserved hypothetical membrane protein. Homology to PJS6w01004232 of Polaromonas sp. JS666 of 53% (gi|54028976|ref|ZP_00361120.1|(NBCI ENTREZ)). InterPro:IPR002035; VWF_A. The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily. Pfam:PF00092; VWA; 1. SMART:SM00327; VWA; 1. PROSITE:PS50234; VWFA; MIP: MIP family channel proteins. No signal peptide present. No. of TMH's: 3 (TMHMM predicted); Conserved h [...]
 
 
 0.730
azo2864
Conserved hypothetical membrane protein. TREMBL:Q9CBL9: 33% identity; 52% similarity The von Willebrand factor is a large multimeric glycoprotein found in bloodplasma. Mutant forms are involved in the aetiology of bleeding disorders. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily Hypothetical protein MAV335. InterPro:IPR002035; VWF_A. Pfam:PF00092; VWA; 1. SMART:SM00327; VWA 2_A_01_02: Multidrug resistance protein Presence of Signal peptide (SignalP predicted) Presence of 3 transmembrane helices (TMHMM predicted); Conserved hypothetical protein.
 
 
 0.730
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.651
cobU
Cobinamide kinase/cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
 
  
 0.638
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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