STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2659Conserved hypothetical secreted protein. Homology to PJS6w01001981 of Polaromonas sp. JS666 of 70% (gi|54030965|ref|ZP_00363100.1|(NBCI ENTREZ)). No domains predicted. signal peptide. no TMHs; Conserved hypothetical protein. (156 aa)    
Predicted Functional Partners:
ybcL
Hypothetical protein TC0109. TREMBL:Q8XTTO: 64% identity, 75% similarity. This entry describes a family of conserved hypothetical proteins with no known function. InterPro:IPR005247; Cons_hypoth481. IPR008914; PEBP. Pfam: PF01161; PBP Absence of signal peptide. Absence of TMH's; Function unclear.
       0.741
trxA2
Putative thioredoxin-disulfide reductase. Homology to trxA (ECs4714) of E. coli of 27%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a dislufide. InterPro: Thioredoxin (IPR006662) no TMHs; Family membership.
       0.494
azo0034
Conserved hypothetical secreted protein. Homology to PP2042 of P. putida of 34% (TrEMBL;Q88L93) Has PF06980:(IPR010727)Protein of unknown function (DUF1302);This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. No TMHs signal peptide present; Conserved hypothetical protein.
  
     0.487
azo0037
Probable exporter of RND superfamily; Putative membrane protein MJ1562. TREMBL:Q88LB6: 47% identity, 63% similarity InterPro:IPR000731; SSD_5TM InterPro: HMGCR/Patched 5TM box Pfam:Patched:Patched family 2A067: efflux transporter putative Signal peptide absent. Presence of 12 transmembrane helices; Family membership.
  
     0.442
azo0035
Conserved hypothetical secreted protein. Homology to PA3421 of P. aeruginosa of 50% (TrEMBL;Q9HYI4) Has (IPR010752)PF07044:Protein of unknown function (DUF1329);This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. No TMHs signal peptide present; Conserved hypothetical protein.
  
     0.438
azo2661
Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs.
       0.437
azo1839
Probable transporter; Putative membrane protein MJ1562. TREMBL:Q88I00: 66% identity, 51% similarity The sterol-sensing domain (SSD) consists of approximately 180 amino acids organized into a cluster of five consecutive membrane-spanning domains and is found in proteins which have key roles in different aspects of cholesterol homeostasis or cholesterol-linked signalling such as sterol-regulated movement or the trafficking of specific cargoes. InterPro:IPR000731; SSD_5TM Found in :IPR003392: Patched family IPR004816: Hydroxymethylglutaryl-CoA reductase (NADPH Pfam:Patched:Patched family [...]
  
     0.431
azo1238
Conserved hypothetical secreted protein. Homology to ebA2217 of Azoarcus sp. EbN1 of 32% (gnl|keqq|eba:ebA2217(KEGG)). C-terminus is not homolog to COG0644. signal peptide present. no TMHS; Conserved hypothetical protein.
  
     0.425
azo2253
Probable exporter of RND superfamily; Putative membrane protein MJ1562. TREMBL:Q88J37: 52% identity, 66% similarity InterPro:IPR001036; Acrflvin_res. IPR000731; SSD_5TM Pfam:Patched:Patched family 2A067: efflux transporter putative Presence of signal peptide (Signal P predicted). Transmembrane helices 12 (TMHMM predicted); Family membership.
  
     0.410
qhpA
Probable quinohemoprotein amine dehydrogenase,alpha subunit. Homology to qhpA of P.putida of 50% (gi|18655859|pdb|1JMZ|A(PDB (RCSB))). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric e [...]
  
     0.408
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.