STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
azo2663Conserved hypothetical peroxiredoxin; Conserve peroxiredoxin. Homology to mll2432 of M. loti of 74% (trembl|Q98IF0). Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic fatty acid and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Pfam: AhpC/TSA family no TMHs. No signal peptide; Family membership. (219 aa)    
Predicted Functional Partners:
trxB1
Putative thioredoxin reductase. Homology to trxB of S. coelicolor of 25% (sprot|TRXB_STRCO). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership.
  
 
 0.869
trxB2
Thioredoxin-disulfide reductase(EC 1.8.1.9). Homology to trxB of E. coli of 71% (sprot|TRXB_ECOLI). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; High confidence in function and specificity.
  
 
 0.869
ahpF
Alkyl hydroperoxide reductase subunit F. Homology to aphF of X. campestris of 71% (sprot|AHPF_XANCH) Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AHPC protein. Pfam: Pyridine nucleotide-disulphide oxidareductase no TMHs; High confidence in function and specificity.
  
  
 0.862
helX
Putative thiol:disulfide oxidoreductase. Homology to helX of R. casulata of 35% Periplasmic protein thiol:disulphide oxidoreductase is involved in the biogenesis of c-type cytochromes as well as in disulphide bond formation in some periplasmic proteins. Tigrfam: dsbE: periplasmic protein thiol:disulfide signal peptide no TMHs; High confidence in function and specificity.
  
 0.851
azo0866
Hypothetical thioredoxin. Homology with BPP3919 of B. parapertussis of 38%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. Tigrfam: dsbE: periplasmic protein thiol:disulfi signal peptide probable 1 TMHs; Family membership.
  
 0.851
azo2154
Conserved hypothetical secreted protein. 33% similarity to TrEMBL Q8XQF8 PROBABLE SIGNAL PEPTIDE PROTEIN [RS05314] [Ralstonia solanacearum (Pseudomonas solanacearum)]. No domains predicted. Signal P reporting signal peptide present. No TMH reported being present; Conserved hypothetical protein.
  
 0.851
mauD
Probable methylamine utilization protein. My be specifically involved in the processing transport and/or maturation of the methylamine dehydrogenase beta-subunit. Tigrfam: dsbE: periplasmic protein thiol:disulfide Signal peptide probable 1 TMHs; Family membership.
  
 0.851
trxA2
Putative thioredoxin-disulfide reductase. Homology to trxA (ECs4714) of E. coli of 27%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a dislufide. InterPro: Thioredoxin (IPR006662) no TMHs; Family membership.
  
 0.851
ccmG
Probable thiol disulfide interchange protein. Involved in disulfide bond formation. Catalyzes a late reductive step in the assembly of periplasmic c-type cytochromes probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity). InterPro: Periplasmic protein thiol:disulfide oxidoreductase DsbE (IPR004799) Interpro: Thioredoxin (IPR006662) Tigrfam: dsbE: periplasmic protein thiol:disulfide axidoreductase, DsbE superfamily signal peptide Probable 1 TMH; Family membership.
  
 0.851
rubA
Probable rubredoxin. Homology to ruba of A. calcoaceticus of 42% (sprot|RUBR_ACIAD). Involved in the hydrocarbon hydroxylating system to convert dodecane to lauric acid, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase. Pfam: Rubredoxin no singal peptide no TMHs; Family membership.
  
  
 0.822
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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