Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo2685GGDEF/EAL/PAS-domain containing protein. (691 aa)    
Predicted Functional Partners:
azo2712
GGDEF/PAS/PAC-domain containing protein,; Conserved hypothetical protein.
 
0.776
azo3061
GGDEF/EAL/PAS/PAC/GAF-domain containing protein.
 
0.760
azo3849
GGDEF/EAL/PAS/PAC-domain containing protein.
 
0.745
amtE
Probable ammonia permease with sensory box/GGDEF domains; Putative ammonium transporter with sensory/GGDEF boxes. TREMBL:Q88M14: 50% identity; 65% similarity; TREMBL:Q7UK31: 46% identity; 58% siilarity InterPro:IPR001633; EAL. IPR000160; GGDEF. IPR001610; PAC. IPR000014; PAS_domain. IPR001905; Ammonium_transpt. IPR003594; ATPbind_ATPase Pfam: PF00563; EAL; PF00990; GGDEF; PF00785; PAC; PF00989; PAS; PF00909; Ammonium_transp SMART SM00267; DUF1; SM00052; DUF2; SM00086; PAC; SM00091; PAS amt: ammonium transporter Nonsecretory protein with signal peptide (SignalP predicted). Presence of 1 [...]
 
0.732
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
  
 0.706
gacS
Putative two-component hybrid sensor and regulator,; Family membership.
 
 0.692
azo2457
Putative sensory box histidine kinase,; Function unclear.
  
 0.689
azo1879
Conserved hypothetical signaling protein. Homology to Daro03001110 of Dechloromonas aromatica of 33% (gi|46141071|ref|ZP_00203851.1|(NBCI ENTREZ)). InterPro: IPR003660 HAMP. IPR000160 GGDEF. Pfam: PF00563 EAL domain. PF00672 HAMP. PF00990 GGDEF domain. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. Signal P reporting signal peptide. TMHMM reporting 3 transmembrane helices; Conserved hypothetical protein.
 
0.633
barA
Putative sensor-regulator protein,; Specificity unclear.
  
 0.633
azo2482
Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...]
  
 0.633
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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