| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ascD | azo2694 | azo3496 | azo2694 | Probable CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase. Homology to ascD of Y. pestis of 41% (sprot|ASCD_YERPE). PARTICIPATES IN THE CONVERSION OF CDP-6-DEOXY-D-GLYCERO- L-THREO-4-HEXULOSE TO 36-DIDEOXY-D-GLYCERO-D-GLYCERO-4-HEXULOSE TOGETHER WITH CDP-6-DEOXY-D-GLYCERO-L-THREO-4-HEXULOSE-3-DEHYDRASE (E1) IN TWO CONSECUTIVE STEPS. THE DETAILED MECHANISM OF E3 IS NOT YET RESOLVED. InterPro: Oxidoreductase FAD and NAD(P)-binding domain (IPR001433); NadH:cytochrome b5 reductase (CBR) (IPR000134); 2Fe-2S Ferredoxin (IPR006057); Phenol hydroylase reductase family (IPR001221) [...] | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | 0.931 |
| ascD | azo2695 | azo3496 | azo2695 | Probable CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase. Homology to ascD of Y. pestis of 41% (sprot|ASCD_YERPE). PARTICIPATES IN THE CONVERSION OF CDP-6-DEOXY-D-GLYCERO- L-THREO-4-HEXULOSE TO 36-DIDEOXY-D-GLYCERO-D-GLYCERO-4-HEXULOSE TOGETHER WITH CDP-6-DEOXY-D-GLYCERO-L-THREO-4-HEXULOSE-3-DEHYDRASE (E1) IN TWO CONSECUTIVE STEPS. THE DETAILED MECHANISM OF E3 IS NOT YET RESOLVED. InterPro: Oxidoreductase FAD and NAD(P)-binding domain (IPR001433); NadH:cytochrome b5 reductase (CBR) (IPR000134); 2Fe-2S Ferredoxin (IPR006057); Phenol hydroylase reductase family (IPR001221) [...] | Conserved hypothetical protein. Homology to BF2580 of Bacteroides fragilis of 47% (gnl|keqq|bfr:BF2580(KEGG)). No domains predicted. No TMHs. No signal peptide. | 0.746 |
| ascD | gumD | azo3496 | azo2246 | Probable CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase. Homology to ascD of Y. pestis of 41% (sprot|ASCD_YERPE). PARTICIPATES IN THE CONVERSION OF CDP-6-DEOXY-D-GLYCERO- L-THREO-4-HEXULOSE TO 36-DIDEOXY-D-GLYCERO-D-GLYCERO-4-HEXULOSE TOGETHER WITH CDP-6-DEOXY-D-GLYCERO-L-THREO-4-HEXULOSE-3-DEHYDRASE (E1) IN TWO CONSECUTIVE STEPS. THE DETAILED MECHANISM OF E3 IS NOT YET RESOLVED. InterPro: Oxidoreductase FAD and NAD(P)-binding domain (IPR001433); NadH:cytochrome b5 reductase (CBR) (IPR000134); 2Fe-2S Ferredoxin (IPR006057); Phenol hydroylase reductase family (IPR001221) [...] | Putative glycosyltransferase; 43% Bact_transf. Pfam:PF02397; Bac_transf; 1. TMhelix:5; Specificity unclear. | 0.401 |
| ascD | rmlA | azo3496 | azo1875 | Probable CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase. Homology to ascD of Y. pestis of 41% (sprot|ASCD_YERPE). PARTICIPATES IN THE CONVERSION OF CDP-6-DEOXY-D-GLYCERO- L-THREO-4-HEXULOSE TO 36-DIDEOXY-D-GLYCERO-D-GLYCERO-4-HEXULOSE TOGETHER WITH CDP-6-DEOXY-D-GLYCERO-L-THREO-4-HEXULOSE-3-DEHYDRASE (E1) IN TWO CONSECUTIVE STEPS. THE DETAILED MECHANISM OF E3 IS NOT YET RESOLVED. InterPro: Oxidoreductase FAD and NAD(P)-binding domain (IPR001433); NadH:cytochrome b5 reductase (CBR) (IPR000134); 2Fe-2S Ferredoxin (IPR006057); Phenol hydroylase reductase family (IPR001221) [...] | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.646 |
| azo2694 | ascD | azo2694 | azo3496 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | Probable CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase. Homology to ascD of Y. pestis of 41% (sprot|ASCD_YERPE). PARTICIPATES IN THE CONVERSION OF CDP-6-DEOXY-D-GLYCERO- L-THREO-4-HEXULOSE TO 36-DIDEOXY-D-GLYCERO-D-GLYCERO-4-HEXULOSE TOGETHER WITH CDP-6-DEOXY-D-GLYCERO-L-THREO-4-HEXULOSE-3-DEHYDRASE (E1) IN TWO CONSECUTIVE STEPS. THE DETAILED MECHANISM OF E3 IS NOT YET RESOLVED. InterPro: Oxidoreductase FAD and NAD(P)-binding domain (IPR001433); NadH:cytochrome b5 reductase (CBR) (IPR000134); 2Fe-2S Ferredoxin (IPR006057); Phenol hydroylase reductase family (IPR001221) [...] | 0.931 |
| azo2694 | azo2695 | azo2694 | azo2695 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | Conserved hypothetical protein. Homology to BF2580 of Bacteroides fragilis of 47% (gnl|keqq|bfr:BF2580(KEGG)). No domains predicted. No TMHs. No signal peptide. | 0.704 |
| azo2694 | azo3189 | azo2694 | azo3189 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | 0.687 |
| azo2694 | azo3193 | azo2694 | azo3193 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | Glycosyltransferase; Might transfer a sugar moiety directly to a lipd acceptor. Putative colanic biosynthesis UDP-glucose lipid carrier transferase. InterPro: Bacterial sugar transferase; Family membership. | 0.944 |
| azo2694 | capD | azo2694 | azo3581 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | Putative capsular polysaccharide biosynthesis protein; 48% Polysac_CapD. Pfam:PF02719; Polysacc_synt_2; 1; High confidence in function and specificity. | 0.908 |
| azo2694 | gumD | azo2694 | azo2246 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | Putative glycosyltransferase; 43% Bact_transf. Pfam:PF02397; Bac_transf; 1. TMhelix:5; Specificity unclear. | 0.940 |
| azo2694 | ligC | azo2694 | azo2536 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | Hypothetical oxidoreductase yrbE (EC 1.-.-.-). TREMBL:Q93PS4:90% identity; 93% similarity. This group of enzymes utilise NADP or NAD, and is known as the GFO/IDH/MOCA family in Swiss-Prot. GFO is a glucose--fructose oxidoreductase, which converts D-glucose and D-fructose into D-gluconolactone and D-glucitol in the sorbitol-gluconate pathway. MOCA is a rhizopine catabolism protein which may catalyze the NADH-dependent dehydrogenase reaction involved in rhizopine catabolism. Other proteins belonging to this family include Gal80, a negative regulator for the expression of lactose and gala [...] | 0.835 |
| azo2694 | mnaA | azo2694 | azo3278 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity. | 0.767 |
| azo2694 | rmlA | azo2694 | azo1875 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.683 |
| azo2694 | rmlB | azo2694 | azo1877 | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | dTDP-glucose 46-dehydratase (EC 4.2.1.46). InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.897 |
| azo2695 | ascD | azo2695 | azo3496 | Conserved hypothetical protein. Homology to BF2580 of Bacteroides fragilis of 47% (gnl|keqq|bfr:BF2580(KEGG)). No domains predicted. No TMHs. No signal peptide. | Probable CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase. Homology to ascD of Y. pestis of 41% (sprot|ASCD_YERPE). PARTICIPATES IN THE CONVERSION OF CDP-6-DEOXY-D-GLYCERO- L-THREO-4-HEXULOSE TO 36-DIDEOXY-D-GLYCERO-D-GLYCERO-4-HEXULOSE TOGETHER WITH CDP-6-DEOXY-D-GLYCERO-L-THREO-4-HEXULOSE-3-DEHYDRASE (E1) IN TWO CONSECUTIVE STEPS. THE DETAILED MECHANISM OF E3 IS NOT YET RESOLVED. InterPro: Oxidoreductase FAD and NAD(P)-binding domain (IPR001433); NadH:cytochrome b5 reductase (CBR) (IPR000134); 2Fe-2S Ferredoxin (IPR006057); Phenol hydroylase reductase family (IPR001221) [...] | 0.746 |
| azo2695 | azo2694 | azo2695 | azo2694 | Conserved hypothetical protein. Homology to BF2580 of Bacteroides fragilis of 47% (gnl|keqq|bfr:BF2580(KEGG)). No domains predicted. No TMHs. No signal peptide. | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | 0.704 |
| azo3189 | azo2694 | azo3189 | azo2694 | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. | 0.687 |
| azo3189 | azo3193 | azo3189 | azo3193 | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | Glycosyltransferase; Might transfer a sugar moiety directly to a lipd acceptor. Putative colanic biosynthesis UDP-glucose lipid carrier transferase. InterPro: Bacterial sugar transferase; Family membership. | 0.907 |
| azo3189 | capD | azo3189 | azo3581 | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | Putative capsular polysaccharide biosynthesis protein; 48% Polysac_CapD. Pfam:PF02719; Polysacc_synt_2; 1; High confidence in function and specificity. | 0.955 |
| azo3189 | gumD | azo3189 | azo2246 | NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. | Putative glycosyltransferase; 43% Bact_transf. Pfam:PF02397; Bac_transf; 1. TMhelix:5; Specificity unclear. | 0.833 |