Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fliSFlagellar protein fliS. The function of this protein in flagellar biosynthesis is unknown, but appears to be regulatory. Might be a chaperon for Flic. InterPro: Flagellar protein FliS fliS: flagellar protein FliS Pfam: Flagellar protein FliS no signal peptide no TMHs; Family membership. (136 aa)    
Predicted Functional Partners:
fliD
Flagellar hook-associated protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
 
 0.997
flgL
Flagellar hook-associated protein 3 (HAP3) (Hook-filament junction protein). no signal peptide no TMHs; High confidence in function and specificity.
 
 
 0.996
fliC3
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.993
flgK
Flagellar hook-filament junction protein 1 (HAP1). no signal peptide no TMHs; High confidence in function and specificity.
 
 
 0.993
fliC1
Putative flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.988
fliC2
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.988
azo2742
Putative negative regulator of flagellin synthesis FlgM; Region start changed from 3024385 to 3024358 (27 bases).
 
 
 0.987
fliI
ATP synthase (EC 3.6.3.14). Probable catalytic subunit of a protein translocase for flagellum-specific export or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage. InterPro: ATP synthase alpha and beta subunit central region Pfam: ATP synthase alpha/beta family no signal peptide no TMHs; High confidence in function and specificity.
 
 
 0.986
fliF
Flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
 
  
 0.983
fliN
Flagellar motor switch protein fliN (Flagellar motor switch protein mopA) (Fragment). FliN is one of three proteins (FliG FliN FliM) that form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins in addition to contacting components of the motor that determine the dirction of flagellar rotation (by similarity). InterPro: Surface presentation of antigens (SPOA) protein, Flagellar motor switch FliN protein Pfam: Surface presentation of antigens (SPOA) protein no signal peptide no TMHs; High confid [...]
 
  
 0.983
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.