STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
erpAConserved hypothetical protein; Required for insertion of 4Fe-4S clusters. (116 aa)    
Predicted Functional Partners:
nifU
Probable nitrogen fixation protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 
 0.950
hscB
Putative co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.797
azo0983
Conserved hypothetical protein. Homology to ne1911 of N. europaea of 67%. InterPro: Glutaredoxin-related protein (IPR004480) TIGR00365: glutaredoxin-related protein no signal peptide no TMHs; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.733
iscU
NifU-related protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.662
azo1593
Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...]
 
 
 
 0.654
nifQ
Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership.
  
  
 0.620
iscS1
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
  
 0.606
iscS2
Probable cysteine desulfurase (NifS protein homolog). Homology to iscS of M. thermophila of 40% (sprot|ISCS_METTE) Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). InterPro: Aminotransferase class-V (IPR000192) Pfam: aminotransferase class-V no signal peptide no TMHs ahpD: alkylhydroperoxidase AhpD; Family membership.
 
  
 0.586
hscA
Probable chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
 
 
 0.564
prfA
Peptide chain release factor; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.531
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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