Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (365 aa)    
Predicted Functional Partners:
thdF
Probable tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 0.837
gidA
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
 
 0.803
azo2773
Conserved hypothetical secreted protein. Homology to ebA988 of Azoarcus sp. EbN1 of 43% (gnl|keqq|eba:ebA988(KEGG)). no domains predicted. signal peptie. no TMHs; Conserved hypothetical protein.
       0.799
nudJ
Conserved hypothetical protein; Putative Nudix hydrolase ymfB (EC 3.6.-.-). mutt: mutator mutT protein; Specificity unclear; Belongs to the Nudix hydrolase family. NudJ subfamily.
  
    0.793
nifS
Cysteine desulphurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
  
 
 0.771
iscS1
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 
 0.771
iscS2
Probable cysteine desulfurase (NifS protein homolog). Homology to iscS of M. thermophila of 40% (sprot|ISCS_METTE) Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). InterPro: Aminotransferase class-V (IPR000192) Pfam: aminotransferase class-V no signal peptide no TMHs ahpD: alkylhydroperoxidase AhpD; Family membership.
  
 
 0.771
azo2804
Adenylyltransferase, putative; Dinucleotide-utilizing enzyme involved in molybdopterin and/or thiamine biosynthesis Belongs to the hesA/moeB/thiF family, by similarity. TIGR00292: thiazole biosynthesis enzyme; High confidence in function and specificity.
    
 0.752
thiS
Thiamine biosynthesis protein ThiS; Putative sulfur transfer protein involved in thimanin biosynsthesis; High confidence in function and specificity.
  
 
  0.735
azo2810
Conserved hypothetical protein; Similar to Rhodanese domain protein, a sulphurtransferase involved in cyanide detoxification. Hypothetical protein slr1261. InterPro: Rhodanese/cdc25 fold; Function unclear.
  
 
 0.688
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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