| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0558 | azo2782 | azo0558 | azo2782 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | 0.790 |
| azo0558 | fdxB | azo0558 | azo0556 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Probable ferredoxin. Homology to fdxB of R. capsulatus of 45% (sprot|FER3_RHOCA) Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership. | 0.898 |
| azo0558 | nifD | azo0558 | azo0539 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogenase molybdenum-iron protein alpha chain (EC 1.18.6.1) (Nitrogenase component I) (Dinitrogenase). The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components: the iron protein and the molybdenum-iron protein; High confidence in function and specificity. | 0.809 |
| azo0558 | nifE | azo0558 | azo0562 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE. Homology to nifE of A. vielandii of 70% (sprot|NIFE_AZOVI). This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). InterPro: Oxidoreductase nitrogenase component 1 (IPR000510) Pfam: Nitrogenease component 1 type oxidoreductase no signal peptide no TMHs; High confidence in function and specificity; Belongs to the NifD/NifK/NifE/NifN family. | 0.948 |
| azo0558 | nifH | azo0558 | azo0538 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Putative nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. | 0.754 |
| azo0558 | nifK | azo0558 | azo0540 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. | 0.829 |
| azo0558 | nifN | azo0558 | azo0561 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Probable nitrogenase iron-molybdenum cofactor biosynthesis protein NifN. Homology to nifN of A. vielandii of 60% (sprot|NIFN_AZOVI). This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). InterPro: Oxidoreductase nitrogenase component 1 (IPR000510) Pfam: Nitrogenease component 1 type oxidoreductase probable signal peptide no TMHs; High confidence in function and specificity; Belongs to the NifD/NifK/NifE/NifN family. | 0.956 |
| azo0558 | nifT | azo0558 | azo0541 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogen fixation protein [nifT],51% identity(72% Similarity) to SwissProt;P09427, TrEMBL;Q93JU8,57% identity. Has PF06988:NifT/FixU protein(IPR009727);This family consists of several NifT and FixU bacterial proteins. The function of NifT is unknown although it is thought that the protein may be involved in biosynthesis of the FeMo cofactor of nitrogenase although perturbation of nifT expression in K. pneumoniae has only a limited effect on nitrogen fixation. No Signal peptide or TMH present; High confidence in function and specificity. | 0.854 |
| azo0558 | nifW | azo0558 | azo0548 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogen fixation protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family. | 0.872 |
| azo0558 | nifX | azo0558 | azo0560 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Conserved hypothetical NifX protein. Homology to nifX of Azotobacter vinelandii of 47% (gi|128328|sp|P14887|NIFX_AZOVI(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs; Conserved hypothetical protein. | 0.952 |
| azo2782 | azo0558 | azo2782 | azo0558 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | 0.790 |
| azo2782 | fdxB | azo2782 | azo0556 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Probable ferredoxin. Homology to fdxB of R. capsulatus of 45% (sprot|FER3_RHOCA) Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership. | 0.775 |
| azo2782 | nifD | azo2782 | azo0539 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Nitrogenase molybdenum-iron protein alpha chain (EC 1.18.6.1) (Nitrogenase component I) (Dinitrogenase). The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components: the iron protein and the molybdenum-iron protein; High confidence in function and specificity. | 0.812 |
| azo2782 | nifE | azo2782 | azo0562 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE. Homology to nifE of A. vielandii of 70% (sprot|NIFE_AZOVI). This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). InterPro: Oxidoreductase nitrogenase component 1 (IPR000510) Pfam: Nitrogenease component 1 type oxidoreductase no signal peptide no TMHs; High confidence in function and specificity; Belongs to the NifD/NifK/NifE/NifN family. | 0.812 |
| azo2782 | nifH | azo2782 | azo0538 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Putative nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. | 0.874 |
| azo2782 | nifK | azo2782 | azo0540 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. | 0.812 |
| azo2782 | nifN | azo2782 | azo0561 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Probable nitrogenase iron-molybdenum cofactor biosynthesis protein NifN. Homology to nifN of A. vielandii of 60% (sprot|NIFN_AZOVI). This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). InterPro: Oxidoreductase nitrogenase component 1 (IPR000510) Pfam: Nitrogenease component 1 type oxidoreductase probable signal peptide no TMHs; High confidence in function and specificity; Belongs to the NifD/NifK/NifE/NifN family. | 0.812 |
| azo2782 | nifT | azo2782 | azo0541 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Nitrogen fixation protein [nifT],51% identity(72% Similarity) to SwissProt;P09427, TrEMBL;Q93JU8,57% identity. Has PF06988:NifT/FixU protein(IPR009727);This family consists of several NifT and FixU bacterial proteins. The function of NifT is unknown although it is thought that the protein may be involved in biosynthesis of the FeMo cofactor of nitrogenase although perturbation of nifT expression in K. pneumoniae has only a limited effect on nitrogen fixation. No Signal peptide or TMH present; High confidence in function and specificity. | 0.760 |
| azo2782 | nifW | azo2782 | azo0548 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Nitrogen fixation protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family. | 0.808 |
| azo2782 | nifX | azo2782 | azo0560 | Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs. | Conserved hypothetical NifX protein. Homology to nifX of Azotobacter vinelandii of 47% (gi|128328|sp|P14887|NIFX_AZOVI(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs; Conserved hypothetical protein. | 0.770 |