STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2785Conserved hypothetical membrane protein. Homology to SC3D11.05C of Streptomyces coelicolor of 33% (trembl|Q9L1F7(SRS)). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting three transmembrane helices. No signal peptide; Conserved hypothetical protein. (624 aa)    
Predicted Functional Partners:
azo0646
Toxin secretion ABC transporter permease and ATP-binding protein; HlyB-family protein. Similar to TREMBL:Q7WBM7 (50% identity); TREMBL:Q9KKL9 (41% identity); SWISSPROT:P18770 (28% identity). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting four transmembrane helices. TC (3.A.1.109.3): LapA adhesin protein exporter, LapB; High confidence in function and specificity.
   
0.855
azo2638
Conserved hypothetical ATPase. Homology to rsc1961 of R. solanacearum of 37% (trembl|Q8XY02). Pfam: Atpase familly associated with various cellular activities (domaine 1 from 300 aa to 499 aa, domaine 2 from 543 to 723 aa). no signal peptide. no TMHs; Conserved hypothetical protein.
   
 0.648
azo3791
Conserved hypothetical ATPase. Homology to MCA0262 of Methylococcus capsulatus of 68% (gi|53756248|gb|AAU90539.1|(NBCI ENTREZ)). InterPro: AAA-protein (ATPases associated with various cellular activities) (IPR003959);AAA ATPase superfamily (IPR003593) Pfam: ATPase family associated with various cellular activities (domaine from 365 aa to 540 aa) no signal peptide. no TMHs; Function unclear.
   
 0.648
atm1
Probable composite transport ATP-binding permease protein. Homology to amt1 of S. cereviciae of 48% (sprot|ATM1_YEAST). COULD BE INVOLVED IN THE TRANSPORT OF yet unknow substrates (probable HEME) FROM THE MITOCHONDRIA TO THE CYTOSOL. InterPro: ABC transporter transmembrane region (IPR001140), ATP/GTP-binding site motif A (P loop) (IPR001687), ABC transporter (IPR003439),AAA_ATPase sperfamily (IPR003593) Pfam: ATP transporter,ABC transporter transmembrane region no signal peptide probable 6 TMHs; Specificity unclear.
  
 
0.608
azo1821
Conserved hypothetical membrane protein. Homology to ebA6882 of Azoarcus sp. EbN1 of 74% (gnl|keqq|eba:ebA6882(KEGG)). Domian structure: 373 aa -599 aa AAA ATPase; 638 aa - 726 aa HATPase_c; 750 aa - 877 aa Rec InterPro: ABC transporter (IPR003439); AAA ATPase superfamily (IPR003593); ABC transporter transmembrane region (IPR001140); ATP/GTP-binding site motif A ((P-loop) (IPR001687); (Response regulator reciver (IPR001789); Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase (IPR003594) Pfam: ABC-transporter, ABC transmembrane region; Response regulator reciver domain. no signal [...]
  
 
0.608
azo2279
Conserved hypothetical protein. Homology to Avin02000067 of Azotobacter vinelandii of 50% (gi|23105742|ref|ZP_00092196.1|(NBCI ENTREZ)). InterPro: Ankyrin-repeat. The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids.The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures [...]
   
 0.604
azo3351
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:O59091 (37% identity); TREMBL:Q7NDM5 (40% identity). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily; High confidence in function and specificity.
  
 
 0.599
dinP
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
     
 0.587
azo3166
Hypothetical Protein,20% identity to TrEMBL;Q9HUK7. Very Bad homology with the hits in the DB over entire length of protein. No substantial good hits available. No signal peptide or TMH reported present.
  
     0.567
azo3521
Conserved hypothetical peptidase. Homology to ebA3686 of Azoarcus sp. EbN1 of 45% (gnl|keqq|eba:ebA3686(KEGG)). Pfam: Peptidase family M48. signal peptide. 1 TMHs; Conserved hypothetical protein.
 
 
   0.567
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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