STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpmAPutative phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (249 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinaseis an enzyme that catalyses the formation of ATP to ADP and viceversa. In the second step of the second phase in glycolysis, 1,3-diphosphoglycerate is converted to 3-phosphoglycerate,forming one molecule of ATP. If the reverse were to occur,one molecule of ADP would be formed. 59% PGK. Pfam:PF00162; PGK; 1; High confidence in function and specificity.
   
 0.993
eno
Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.989
pgi
Glucose-6-phosphate isomerase 1(EC 5.3.1.9) (GPI 1)(Phosphoglucose isomerase 1)(PGI 1)(Phosphohexose isomerase 1) (PHI 1). Enzyme involved in glycolysis and in gluconeogenesis.Catalytic activity: d-glucose 6-phosphate = d-fructose 6- phosphate.Belongs to the gpi family. 39% G6P_Isomerase. Pfam:PF00342; PGI; 1; High confidence in function and specificity.
  
 
 0.972
fba
Putative fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
   
 
 0.968
tim
Putative triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.954
gpmB
Probable phosphoglycerate mutase GpmB (phosphoglyceromutase) 0(Pgam). Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 31% PG/BPGM_mutase. Pfam:PF00300; PGAM; 1; High confidence in function and specificity.
  
 
0.935
azo2807
Conserved hypothetical protein; Homology to peptidase, M23/M37 family InterPro: Peptidase family M23/M37.
  
    0.908
tkt
Putative transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 0.904
serA
D-3-phosphoglycerate dehydrogenase, SerA, is involved in the pathway of serine biosynthesis. Similar to sprot|SERA_ECOLI (61%). InterPro (PF00389): D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain InterPro (PF01842): ACT domain InterPro (PF02826): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; High confidence in function and specificity.
  
 0.884
ttuD
Putative hydroxypyruvate reductase. Degrades an unidentified toxic product from the first step of tartrate degradation. Involved in the second step of the tartrate degradation pathway. 59% MOFRL.IPR005346; UPF0125. Pfam:PF05161; MOFRL; 1.PF03658; UPF0125; 1. Signal peptide present; High confidence in function and specificity.
     
 0.854
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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