STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grxCProbable glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (90 aa)    
Predicted Functional Partners:
azo1411
Conserved hypothetical ribonucleoside reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.966
secB
Protein export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
  
 0.953
azo2810
Conserved hypothetical protein; Similar to Rhodanese domain protein, a sulphurtransferase involved in cyanide detoxification. Hypothetical protein slr1261. InterPro: Rhodanese/cdc25 fold; Function unclear.
  
    0.935
msrA
Putative peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.821
hlyU
Putative transcriptional activator, ArsR family,; High confidence in function and specificity.
       0.707
azo0983
Conserved hypothetical protein. Homology to ne1911 of N. europaea of 67%. InterPro: Glutaredoxin-related protein (IPR004480) TIGR00365: glutaredoxin-related protein no signal peptide no TMHs; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.695
gpsA
Probable NAD-dependent glycerol-3-phosphate dehydrogenase [NAD(P)+]. Homology to gpsA of B. subtilis of 41% (SWISSPROT:GPDA_BACSU). NAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate. InterPro: NAD-dependent glycerol-3-phosphate dehydrogenase (IPR006109) Pfam: NAD-dependent glycerol-3-phosphate dehydrogeanse signal peptide no TMHs apbA_panE: 2-dehydropantoate 2-reductas; High confidence in function and specificity.
  
  
 0.692
metH
Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.688
ribAB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.655
azo2813
Conserved hypothetical secreted protein. Homology to CV1128 of Chromobacterium violaceum of 43% (trembl:Q7NYZ4). Has Signal Peptide. Has PF06347, Protein of unknown function (DUF1058);IPR010466; This family consists of several hypothetical bacterial proteins of unknown function. No TMHs; Conserved hypothetical protein.
       0.625
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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