STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comFHypothetical protein yhgH. Members of PRT family are catalytic and regulatory proteins involved in nucleotide synthesis and salvage. The name PRT comes from phosphoribosyltransferase enzymes, which carry out phosphoryl transfer reactions on PRPP, an activated form of ribose-5-phosphate SPROT:P46846: 33% identity, 51% similarity InterPro; IPR000836; PRtransferase. Pfam; PF00156; Pribosyltran; 1 Absence of Signal peptide and Transmembrane helices PPR: pentatricopeptide repeat domain; High confidence in function and specificity. (230 aa)    
Predicted Functional Partners:
comA
Putative DNA uptake/competence protein; Competence protein comA. Essential for natural transformation. Could be a transporter involved in DNA uptake. InterPro: DNA internalization-related competence protein ComEC/Rec2 function: transporter activity TREMBL:Q82SD2: 38% identity,50% similarity. InterPro:IPR001279; Blactmase-like. IPR004477; ComEC_N-term. IPR004797; ComEC_Rec2. Pfam PF03772; Competence; 1. PF00753; Lactamase_B; 1. TIGRFAMs:TIGR00360; ComEC_N-term; 1. TIGR00361; ComEC_Rec2; ComEC_Rec2: DNA internalization-relate TMHMM predicted 8 transmembrane helices; High confidence in fu [...]
 
  
 0.935
drpA
Putative DNA processing protein DrpA (Smf protein). Homology to drpA of H. influcenzae The SMF family (DNA processing chain A, dprA) are a group of bacterial proteins. In Helicobacter pylori, dprA is required for natural chromosomal and plasmid transformation InterPro: SMF family Tigerfam: dprA: DNA processing protein DprA,putative Pfam SMF family no signal peptide no TMHs; Family membership.
 
 
 0.927
azo3736
Conserved hypothetical protein. Homology to rsc0338 of R. solanacearum of 64% (trembl|Q8Y2J7). Probable Mg(2+) chelatase family protein. InterPro: Mg chelatase-related protein (IPR004482); MCM family (IPR001208); AAA ATPase superfamily (IPR003593); Magnesium chalatase, chlI subunit (IPR000523); TypeI antifreeze protein (IPR000104). no signal peptide. no TMHs. TIGR00368: Mg chelatase-related protein; Family membership.
 
  
 0.856
flgC
Flagellar basal-body rod protein flgC. The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity.
   
   0.834
trmL
tRNA/rRNA methylase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
       0.800
tyrA
Prephenate dehydrogenases are involved in tyrosine biosynthesis. Similar to trembl|Q7NSL5 (54%) and to trembl|Q82XD9 (47%). Pfam: PDH, Prephenate dehydrogenase. TMHMM reporting one Tmhelix. SignalP reporting Signal peptide; Specificity unclear.
   
  
 0.787
barA
Putative sensor-regulator protein,; Specificity unclear.
  
  
 0.756
azo2482
Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...]
  
  
 0.756
gacS
Putative two-component hybrid sensor and regulator,; Family membership.
  
  
 0.756
radC1
DNA repair protein radC homolog, 64% Idnentity to SwisProt;Q82UL9,(58%) to Q8XWN0. TrEMBL;Q7NTH5(60% Identity) Signal Peptide Present Has PF04002, RadC, DNA repair protein;IPR001405: RadC plays a role in repair of DNA damage after UV and X-ray irradiation in prokaryotes. The E. coli radC gene encodes a RecG-like DNA recombination/repair function. RadC may function specifically in recombinational repair that is associated with the replication fork; Belongs to the UPF0758 family.
 
    0.745
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.