STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2850Putative sugar transport protein; Proline/betaine transporter (Proline porter II) (PPII). STRETCH-INACTIVATED PROLINE/BETAINE TRANSPORTER. PROP IS BOTH AN OSMOSENSOR AND AN OSMOREGULATOR WHICH IS AVAILABLE TO PARTICIPATE EARLY IN THE BACTERIAL OSMOREGULATORY RESPONSE. MEDIATES THE ACTIVE ACCUMULATION OF SOLUTES SUCH AS PROLINE GLYCINE BETAINE STACHYDRINE PIPECOLIC ACID ECTOINE AND TAURINE.PROBABLE MtbA PROTEIN 2A0106: citrate-proton symport; Specificity unclear. (545 aa)    
Predicted Functional Partners:
azo2849
Conserved hypothetical membrane protein. Homology to AQ_563 of Aquifex aeolicus of 37% (trembl|O66835(SRS)). Has IPR003660;PF00672;HAMP domain:This domain is known as the HAMP domain for histidine kinases, adenylyl cyclases,methyl binding proteins and phosphatases. It is found in bacterial sensor and chemotaxis proteins and in eukaryotic histidine kinases. The bacterial proteins are usually integral membrane proteins and part of a two-component signal transduction pathway. Has IPR000160(GGDEF)domain,this domain is found linked to a wide range of non-homologous domains in a variety of b [...]
       0.518
azo2851
Conserved hypothetical glycerophosphoryl diester phosphodiesterase. Homology to TdenA01001091 of Thiobacillus denitrificans of 66% (gnl|keqq|mca:MCA1922(KEGG)).InterPro: Glycerophosphoryl diester phosphodiesterase (IPR004129). Pfam: Glycerophosphoryl diester phosphodiesterase. signal peptide. no TMHs.
       0.503
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
     
 0.482
pabB
Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear.
   
 
 0.453
aas
AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...]
    
 0.428
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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