Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
azo2851Conserved hypothetical glycerophosphoryl diester phosphodiesterase. Homology to TdenA01001091 of Thiobacillus denitrificans of 66% (gnl|keqq|mca:MCA1922(KEGG)).InterPro: Glycerophosphoryl diester phosphodiesterase (IPR004129). Pfam: Glycerophosphoryl diester phosphodiesterase. signal peptide. no TMHs. (449 aa)    
Predicted Functional Partners:
glpK
Probable glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
  
 0.882
glpA
Putative glycerol-3-phosphate dehydrogenase. Homology to glpA of B. hermsir of 38% (trembl|Q84I21) FAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the conversion of glycerol-3-phosphate into dihydroxyacetone phosphate: sn-glycerol-3-phosphate + acceptor = glycerone phosphate + reduced acceptor. InterPro: D-amino acid oxidase (IPR000927) Pfam: FAD dependent oxidoreductase no signal peptide no TMHs gidA: glucose-inhibited division prot; Family membership.
  
 0.808
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (PGP synthase). It catalyses the conversion of CDP-diacylglycerol and glycerol-3-phosphate to CMP and 3-(3-phosphatidyl)-glycerol 1-phosphate in the commited step to the synthesis of acidic phospholipids. It is an integral membrane protein. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. Entry name :-SWISSPROT:PGSA_ECOLI Prim. accession # P06978 Identities = 50% InterPro IPR000462; CDP-OH_P_trans. I [...]
   
 0.637
azo0663
Probable CDP-alcohol phosphatidyltransferase family protein; Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol. Entry name Q8PQ18 Primary accession number: Q8PQ18 InterPro IPR000462; CDP-OH_P_trans. Pfam PF01066; CDP-OH_P_transf; 1. Identities = 114/203 (56%),Prediction: Signal peptide Signal peptide probability: 0.988 Number of predicted TMHs: 3; Family membership.
   
 0.612
azo3855
Alkaline phosphatase (EC 3.1.3.1) (ALP)is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH.It is found in nearly all living organisms,with the exception of some plants. 30% Alk_phosphtse.Alkaline phosphatase family Pfam:PF00245; alk_phosphatase; 1. Signal peptide present; High confidence in function and specificity.
  
 
 0.610
ugpQ
Probable glycerophosphodiester phosphodiesterase. Homology to ugpQ of E. coli of 45% (sprot|UGPQ_ECOLI). GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE HYDROLYZES DEACYLATED PHOSPHOLIPIDS TO G3P AND THE CORRESPONDING ALCOHOLS. Pfam: Glycerophosporyl diester phosphodiesterase no signal peptide; High confidence in function and specificity.
     
 0.576
azo0484
FHA domain containing protein. Best similarity to SWISSPROT: sprot|REPB_AGRRH (9% Agrobacterium rhizogenes,possible replication protein b) Pfam: PF00211 Adenylate and Guanylate cyclase catalytic domain. SMART: SM00240 FHA Forkhead associated domain.
   
 
 0.533
azo3620
Putative adenylate/ guanylate cyclase,; Function unclear.
   
 
 0.533
azo0628
Putative adenylate/guanylate cyclase,; Conserved hypothetical protein.
    
 
 0.522
azo2099
Conserved hypothetical secreted protein. Homology to xac2776 of X. axonopodis of 50% (trembl|Q8PIW9). Pfam: DUF839 This family consists of several bacterial proteins of unknown function. signal peptide. no TMHs; Conserved hypothetical protein.
  
 
 0.522
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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