STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
estBProbable carboxylesterase. Homology to estB of P. flourescens of 41% (sprot|EST2_PSEFL). Hydrolyzes carboxylic ester bonds with relatively broad substrate specificity. InterPro: Phospholipase/Carboxylesterase(IPR003140); Esterase/lipase/ thioesterase family acitve site (IPR000379) Pfam: Phospolipase/Carboxylesterase no signal peptide no TMHs; High confidence in function and specificity. (227 aa)    
Predicted Functional Partners:
dnaN
DNA-directed DNA polymerase; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of repl [...]
    
 0.744
mogA
Molybdopterin biosynthesis mog protein. Involved in the biosynthesis of a demolybdo-cofactor (molybdopterin) necessary for molybdo-enzymes (By similarity). InterPro: Molybdenum cofactor biosynthesis protein TIGRFAM: molyb_syn: molybdenum cofactor synthesis; High confidence in function and specificity.
 
    0.726
glpK
Probable glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
    
 
 0.546
azo2856
Conserved hypothetical membrane protein. Homology to PA4104 of Pseudomonas aeruginosa of 46% (trembl|Q9HWS4(SRS)). No domains predictec. no signal peptide. 4 TMHs; Conserved hypothetical protein.
       0.512
boxA
Benzoyl-CoA oxygenase component A. 84% 4Fe4S_ferredoxin. IPR001709; FPN_cyt_redctse. IPR001433; Oxred_FAD/NAD(P). Pfam:PF00037; Fer4; 2. PF00175; NAD_binding_1; 1; High confidence in function and specificity.
     
  0.506
azo2854
Conserved hypothetical protein. Homology to PA3283 of P.aeruginosa of 54% (trembl:Q9HYW0). Has PF05114,Protein of unknown function (DUF692);IPR007801:This family consists of several uncharacterised bacterial proteins. No signal peptide or TMH present.
       0.475
azo2855
Conserved hypothetical protein. Homology to PP2399 of P.putida of 36% (trembl:Q88K92). No domains predicted. No TMHs. No signal peptide.
       0.475
sigX
Putative RNA polymerase sigma factor, Myxococcus xanthus carQ; Alcaligenes eutrophus plasmid pMOL28-encoded cnrH; Escherichia coli fecI; Pseudomonas syringae hrpL; rpoE from Escherichia coli, Salmonella typhimurium and Haemophilus influenzae; Streptomyces coelicolor sigE; and Bacillus subtilis sigma factors sigV, sigX, sigY and sigZ; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
       0.475
azo2858
Conserved hypothetical protein. Homology to CV2972 of C.violaceum of 51% (trembl:Q7NTT1). No domains predicted. No TMHs. No signal peptide.
       0.475
azo3762
Hypothetical patatin-like protein. Homology to all2302 of Anabaena sp. of 20% (trembl|Q8YUN7). Pfam: Patatin. PATATIN MAY HAVE A DUAL ROLE AS A SOMATIC STORAGE PROTEIN AND AS AN ENZYME INVOLVED IN HOST RESISTANCE. THIS TUBER PROTEIN REPRESENTS APPROXIMATELY 40% OF THE TOTAL PROTEIN IN MATURE TUBERS. InterPro: Patatin (IPR002641). no signal peptide. no TMHs.
 
  
  0.470
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.