STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2863Conserved hypothetical serine protease. Homology to PJS6w01004229 of Polaromonas sp. JS666 of 53% (gi|54028973|ref|ZP_00361117.1|(NBCI ENTREZ)). Interpro: HtrA/DegQ protease family (IPR001940); Serine protease,trypsine family (IPR001254). Pfam: Typsin. probable signal peptide. no TMHs; Conserved hypothetical protein. (260 aa)    
Predicted Functional Partners:
glpK
Probable glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.764
rseA
Putative sigma-E factor, negative regulatory protein,; High confidence in function and specificity.
  
 
 0.758
azo2860
Conserved hypothetical membrane protein. Homology to PJS6w01004232 of Polaromonas sp. JS666 of 53% (gi|54028976|ref|ZP_00361120.1|(NBCI ENTREZ)). InterPro:IPR002035; VWF_A. The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily. Pfam:PF00092; VWA; 1. SMART:SM00327; VWA; 1. PROSITE:PS50234; VWFA; MIP: MIP family channel proteins. No signal peptide present. No. of TMH's: 3 (TMHMM predicted); Conserved h [...]
 
   
 0.726
azo2861
Hypothetical protein Rv1480/MT1527/Mb1516. TREMBL:Q7MUE8: 33% identity, 52% similarity. This domain is found in a family of prokaryotic proteins that have no known function. Proteins belonging to this family include hypothetical proteins from eubacteria and archaebacteria. Some of these proteins also contain the Von Willebrand factor, type A domain InterPro: IPR002881; DUF58. Pfam: PF01882; DUF58 Absence of transmembrane helices (TMHMM predicted) cmk: cytidylate kinase; Specificity unclear.
       0.691
moxR2
MoxR protein, putative; MoxR protein (MxaR protein). MAY BE INVOLVED IN THE REGULATION OF FORMATION OF ACTIVE METHANOL DEHYDROGENASE. TREMBLnew:CAE55395: 54% identity, 71% similarity InterPro:IPR003593; AAA_ATPase. IPR000523; Mg_chelatse_chII. Pfam PF01078; Mg_chelatase; 1. SMART SM00382; AAA; 1 InterPro IPR003593; AAA_ATPas ruvB: Holliday junction DNA helicase Ru; High confidence in function and specificity.
       0.690
boxA
Benzoyl-CoA oxygenase component A. 84% 4Fe4S_ferredoxin. IPR001709; FPN_cyt_redctse. IPR001433; Oxred_FAD/NAD(P). Pfam:PF00037; Fer4; 2. PF00175; NAD_binding_1; 1; High confidence in function and specificity.
  
  
  0.567
azo3768
Putative catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
    
 0.562
azo1728
Conserved hypothetical secreted protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.
    
 
 0.521
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 
   0.519
azo2638
Conserved hypothetical ATPase. Homology to rsc1961 of R. solanacearum of 37% (trembl|Q8XY02). Pfam: Atpase familly associated with various cellular activities (domaine 1 from 300 aa to 499 aa, domaine 2 from 543 to 723 aa). no signal peptide. no TMHs; Conserved hypothetical protein.
  
 
 0.517
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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