Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prlCOligopeptidase A counts to the Thimet oligopeptidase family which cleave medium sized peptides. Similar to trembl|Q7VZC9 (49%), to trembl|Q9JX57 (48%) and to sprot|OPDA_ECOLI (51%). Pfam (PF01432): Peptidase family M3; Specificity unclear. (688 aa)    
Predicted Functional Partners:
azo2878
Conserved hypothetical protein; Low similiraty to glutaredoxin protein Grx. Has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase.Reduces low molecular weight disulfides and proteins (by similarity). Hypothetical protein yjbD. Signal peptide; Function unclear.
       0.815
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 
 0.555
azo2876
Conserved hypothetical membrane protein. Homology to cv3790 of C. violaceum of 36% (cvi:CV3790(KEGG). no domains predicted. no signal peptide. 6 TMHs; Conserved hypothetical protein.
       0.536
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
  
  0.526
xdhB
Xanthine dehydrogenase (subunit B) InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus; High confidence in function and specificity.
   
   0.428
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
     
  0.410
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
     
  0.410
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.