STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepPXaa-Pro aminopeptidase,; Specificity unclear. (448 aa)    
Predicted Functional Partners:
ubiH
Probable 2-octaprenyl-6-methoxyphenol hydroxylase oxidoreductase protein; ubiH; aromatic-ring hydroxylase (flavoprotein monooxygenase) Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone. Ubiquinone biosynthesis pathway, by similarity; High confidence in function and specificity.
 
  
 0.885
pepD
Probable aminoacyl-histidine dipeptidase (EC 3.4.13.3) (Xaa-His dipeptidase) (X-His dipeptidase) (Beta-alanyl-histidine dipeptidase) (Carnosinase) (Peptidase D). Homology to pepD of E. coli of 44%. THIS DIPEPTIDASE HAS SPECIFICITY FOR THE UNUSUAL DIPEPTIDE BETA-ALANYL-L-HISTIDINE. InterPro: Peptidase family M20/M25/M40 (IPR002933) Pfam: Peptidase family M20/M25/M40 no signal peptide no TMHs; High confidence in function and specificity.
  
 
 0.815
azo2889
Nucleotidyltransferase; Specificity unclear.
       0.811
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.743
azo2888
Conserved hypothetical protein. Homology to ne0191 of N. europaea of 61% (trembl|Q82XR3). Pfam: DUF227. no signal peptide. no TMHs.
       0.741
aroK
Probable shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
    
  0.698
dusB
Conserved hypothetical tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
 
   
 0.675
hemF
HemF protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
   
 0.665
gcvT
Glycine cleavage T proteins are part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein Similar to sprot|GCST_NITEU (60%). Pfam: Glycine cleavage T-protein (aminomethyltransferase) TIGRfam (TIGR00528): Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity.
  
 0.644
azo2893
Putative fis-like DNA-binding protein, 57% Identity to SwissProt;Q8Y231,TrEMBL;Q7P0M2(58% Identity). Has PF02954, Bacterial regulatory protein, Fis family;IPR002197 HTH_Fis; The Factor for Inversion Stimulation (FIS) protein is a regulator of bacterial functions, and binds specifically to weakly related DNA sequences. It activates ribosomal RNA transcription, and is involved in upstream activation of rRNA promoters. The protein has been shown to play a role in the regulation of virulence factors in both Salmonella typhimurium and Escherichia coli. Some of its functions include inhibiti [...]
       0.624
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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