STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2893Putative fis-like DNA-binding protein, 57% Identity to SwissProt;Q8Y231,TrEMBL;Q7P0M2(58% Identity). Has PF02954, Bacterial regulatory protein, Fis family;IPR002197 HTH_Fis; The Factor for Inversion Stimulation (FIS) protein is a regulator of bacterial functions, and binds specifically to weakly related DNA sequences. It activates ribosomal RNA transcription, and is involved in upstream activation of rRNA promoters. The protein has been shown to play a role in the regulation of virulence factors in both Salmonella typhimurium and Escherichia coli. Some of its functions include inhibiti [...] (78 aa)    
Predicted Functional Partners:
dusB
Conserved hypothetical tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
  
  
 0.979
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
   0.835
dusC
Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.
  
  
 0.819
azo3061
GGDEF/EAL/PAS/PAC/GAF-domain containing protein.
    
 
 0.754
amtE
Probable ammonia permease with sensory box/GGDEF domains; Putative ammonium transporter with sensory/GGDEF boxes. TREMBL:Q88M14: 50% identity; 65% similarity; TREMBL:Q7UK31: 46% identity; 58% siilarity InterPro:IPR001633; EAL. IPR000160; GGDEF. IPR001610; PAC. IPR000014; PAS_domain. IPR001905; Ammonium_transpt. IPR003594; ATPbind_ATPase Pfam: PF00563; EAL; PF00990; GGDEF; PF00785; PAC; PF00989; PAS; PF00909; Ammonium_transp SMART SM00267; DUF1; SM00052; DUF2; SM00086; PAC; SM00091; PAS amt: ammonium transporter Nonsecretory protein with signal peptide (SignalP predicted). Presence of 1 [...]
   
 
 0.747
azo2712
GGDEF/PAS/PAC-domain containing protein,; Conserved hypothetical protein.
    
 
 0.739
azo3849
GGDEF/EAL/PAS/PAC-domain containing protein.
    
 
 0.739
azo0652
Conserved hypothetical GGDF domain protein. Homology to CV0310 of Chromobacterium violaceum of 34% (trembl|Q7P1A3). Has IPR003660_HAMP,SMART;SM00304:This domain is known as the HAMP domain for histidine kinases,adenylyl cyclases, methyl binding proteins and phosphatases. It is found in bacterial sensor and chemotaxis proteins and in eukaryotic histidine kinases. The bacterial proteins are usually integral membrane proteins and part of a two-component signal transduction pathway. Has IPR000160_GGDEF(SMART;SM00267);This domain is found linked to a wide range of non-homologous domains in [...]
    
 
 0.718
azo1476
Conserved hypothetical membrane protein.
    
 
 0.718
azo1879
Conserved hypothetical signaling protein. Homology to Daro03001110 of Dechloromonas aromatica of 33% (gi|46141071|ref|ZP_00203851.1|(NBCI ENTREZ)). InterPro: IPR003660 HAMP. IPR000160 GGDEF. Pfam: PF00563 EAL domain. PF00672 HAMP. PF00990 GGDEF domain. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. Signal P reporting signal peptide. TMHMM reporting 3 transmembrane helices; Conserved hypothetical protein.
    
 
 0.718
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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