STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2909ABC transporter permease; Similar to TREMBL:Q82VH0 (64% identity); TREMBL:Q9HTW0 (63% identity); TREMBL:Q8FZX1 (64% identity). TMHMM predicting seven transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily; Specificity unclear. (394 aa)    
Predicted Functional Partners:
azo2910
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
 
 
0.938
azo2911
Membrane fusion protein; HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q8ZLD9 (56% identity); TREMBL:Q8VR08 (56% identity). Pfam (PF00529): HlyD family secretion protein. SignalP reporting signal peptide. TC (8.A.1): The Membrane Fusion Protein (MFP) Family; Family membership.
 
     0.933
azo2908
Putative TetR family transcriptional regulator,; Family membership.
       0.774
oprM3
Probable outer membrane efflux protein. Homology to oprM of P. aeruginosa of 47%. Component of an efflux system that confers multidrug or multible antibiotic resistence. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHs; Family membership.
 
   
 0.708
azo0039
Conservd hypothetical protein, 79% identity(85% similarity) to TrEMBL;Q88GU7. Has PF02566, OsmC-like protein; IPR003718; Osmotically inducible protein C (OsmC) (P23929) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein (O68390) that has a novel pattern of oxidative stress regulation. Has PF02624, YcaO-like fatty acid binding protein;IPR003776, DUF181;This is a family of proteins of unknown function.
  
  
 0.563
nfsA
Putative oxygen-insensitive NADPH nitroreductase. Homology to snrA of S. typhimurium of 37% (sprot|NFSA_SALTY) REDUCTION OF NITROAROMATIC COMPOUNDS USING NADH. REDUCES NITROFURAZONE BY A PING-PONG BI-BI MECHANISM POSSIBLY TO GENERATE A TWO-ELECTRON TRANSFER PRODUCT. MAJOR COMPONENT OF THE OXYGEN- INSENSITIVE NITROREDUCTASE ACTIVITY IN E.COLI. Pfam: Nitroreductase family no signal peptide no TMHs; Family membership; Belongs to the flavin oxidoreductase frp family.
  
  
 0.524
azo3524
Conserved hypothetical nitroreductase. Homology to cv1555 of C. violaceum of 72% (trembl|Q7NXS1). Involved in the reduction of nitrogen containing compounds. InterPro: Nitroreductase family (IPR000415). Pfam: Nitroreductase family. no signal peptide. no TMHs; Conserved hypothetical protein.
  
  
 0.524
nosF
Copper transport ATP-binding protein nosF.INVOLVED IN COPPER PROCESSING/TRANSPORT.Part of the ABC transporter complex nosDFY involved in copper import. 3% ABC_tran; 1. InterPro:IPR003593; AAA_ATPase. IPR003439; ABC_transporter. InterPro:PS50101:ATP/GTP-binding site motif A (P-loop). InterPro:SM00382:AAA ATPase superfamily; High confidence in function and specificity.
 
 0.523
wzm
Putative permease component of an ABC polysaccharide exporter; 51% ABC_transpt2. Pfam:PF01061; ABC2_membrane; 1. TMhelix:6. Non-secretory protein; Specificity unclear.
    
  0.513
azo0835
Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership.
  
  
 0.464
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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