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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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azo2910ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...] (922 aa)    
Predicted Functional Partners:
azo2911
Membrane fusion protein; HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q8ZLD9 (56% identity); TREMBL:Q8VR08 (56% identity). Pfam (PF00529): HlyD family secretion protein. SignalP reporting signal peptide. TC (8.A.1): The Membrane Fusion Protein (MFP) Family; Family membership.
 
   
 0.947
azo2909
ABC transporter permease; Similar to TREMBL:Q82VH0 (64% identity); TREMBL:Q9HTW0 (63% identity); TREMBL:Q8FZX1 (64% identity). TMHMM predicting seven transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily; Specificity unclear.
 
 
0.946
macB
ATP-binding/permease fusion ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
    
 0.892
wzm
Putative permease component of an ABC polysaccharide exporter; 51% ABC_transpt2. Pfam:PF01061; ABC2_membrane; 1. TMhelix:6. Non-secretory protein; Specificity unclear.
    
 0.872
ugpB
Glycerol-3-phosphate-binding periplasmic protein precursor. SN-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system ugpACE. 30% SBP_bac_1.IPR006061; SBP_dom1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present; High confidence in function and specificity.
     
 0.861
yhbG
Probable ABC transporter ATP-binding protein HI1148. ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. TREMBL:Q7NST9: 64% identity,75% similarity InterPro: IPR003593; AAA_ATPase. IPR003439; ABC_transporter. IPR000767; Disease_resist. IPR003016; Lipoyl_BS. Pfam PF00005; ABC_tran; 1 mobB: molybdopterin-guanine dinucleoti TMH's present 0; High confidence in function and specificity.
    
  0.853
dppD
Putative dipeptide transport system, ATP-binding protein; Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide transport membrane protein, DppD in E.coli Probably responsible for energy coupling to the transport system; Specificity unclear.
  
 
 0.848
dppF
Hypothetical ABC transporter ATP-binding protein yliA. PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YLIABCD. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q82S74: 52% identity, 64% similarity. InterPro: IPR003593; AAA_ATPase. No signal peptide No transmembrane helices. IPR003439; ABC_transporter. IPR010066; Oligo_HPY. Pfam:PF00005; ABC_tran; 2. ProDom: PD000006; ABC_transporter; 1. SMART:SM00382; AAA; 2. TIGRFAMs TIGR01727; oligo_HPY mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity.
  
 
 0.848
azo0422
Hypothetical protein; SPROT:P37718: 26% identity, 43% similarity Cellulose synthase operon protein C precursor. Required for maximal bacterial cellulose synthesis. InterPro: STAS domain. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. InterPro:IPR008410; BCSC_C. IPR003921; Cell_synth_C. Pfam:PF05420; BCSC_C; 1. ant_ant_sig: anti-anti-sigma factor No signal peptide present SignalP pr [...]
    
  0.840
azo0811
Conserved hypothetical protein. Homology to rsc2957 of R. solanacearum of 42% (trembl|Q8XV74). Pfam: STAS domain The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. no signal peptide no TMHs.
    
  0.840
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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