STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tupBProbable tungstate permease protein. Homology to tupB of E. acidaminophilum of 40% (tremble: Q93KD5) Permase of an abc-transport system involved in transport of oxyanions. no signal peptide probable 5 TMHs; Family membership. (234 aa)    
Predicted Functional Partners:
tupC
Probable ATP-binding component of tungstate ABC transporter. Homology to tupC of E. acidaminophilum of 40% (tremble: Q93KD4). PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR tungstate. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. Pfam: ABC transporter Interpo: ABC-transporter (IPR003439), AAA-ATPase (IPR003593), ATP/GTP-binding site motif A (loopP) (IPR001687) no signal peptide no TMHS; Family membership.
  
  0.984
azo3832
Putative ABC-type tungstate transport system,permease component; Function unclear.
 
  
 0.931
azo3843
Putative exported protein.SignalP reporting signal peptice. Most likely cleavage site between pos. 27 and 28: AHA-AP; Function unclear.
 
  
 0.931
azo3833
31% HTH_9; 1. InterPro: IPR003725; ModE:Molybdenum-binding protein N-terminal. ModE are involved in molybdenum transport.These proteins acts both as a repressor and activator of the mod and moa operons,respectively, depending on the properties of the binding site; High confidence in function and specificity.
 
 
 0.801
fdhD
Putative formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
     0.792
torD
Putative Chaperone protein TorD. Homology to torD of E. coli of 23% (sprot|TORD_ECOLI). This family consists of several bacterial TorD proteins. Many prokaryotic molybdoenzymes, for example the TMAO reductase (TorA) of Escherichia coli, require the insertion of a bis(molybdopterin guanine dinucleotide) molybdenum (bis(MGD)Mo) cofactor in its catalytic site to be active and translocated to the periplasm. The TorD chaperone increases apoTorA activation up to four-fold, allowing maturation of most of the apoprotein. Therefore TorD is involved in the first step of TorA maturation to make i [...]
 
    0.787
azo3490
Conserved hypothetical protein. Homology to ebA2947 of Azoarcus sp. EbN1 of 58% (gnl|keqq|eba:ebA2947(KEGG)). No domains predicted. No signal peptide. No TMHs.
 
    0.786
fdhA2
Probable formate dehydrogenase alpha subunit. Homology to fdha of W. succinogenes of 44% (pir|S18213) The formate dehydrogenase catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain singal peptide no TMHs; High confidence in function and specificity.
 
     0.775
modE
Putative molybdenum transport protein; 80% ModE.IPR004606; Mop.IPR008995; MOP_like.IPR005116; TOBE.Molybdenum-binding protein N-terminal. Pfam:PF02573; HTH_9; 1.PF03459; TOBE; 2. TIGRFAMs:TIGR00637; ModE_repress; 1:ModE molybdate transport.TIGR00638; Mop; 2; High confidence in function and specificity.
    
 0.774
modG
Putative molybdenum-pterin-binding-protein; 80% Mop.IPR008995;MOP_like.IPR005116;TOBE.InterPro: Molybdenum-pterin binding domain. Mop: molybdenum-pterin binding domain Pfam: PF03459; TOBE; 2. TIGRFAMs:TIGR00638; Mop; 2; High confidence in function and specificity.
    
 0.774
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.