STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2928Conserved hypothetical protein. Homology to Rgel02003612 of Rubrivivax gelatinosus PM1 of 51% (gi|47572157|ref|ZP_00242203.1|(NBCI ENTREZ)). Pfam: This family ThiS (thiaminS) is a 66 aa protein involved in sulphur transfer. This family of proteins have two conserved Glycines at the COOH terminus. MoaD, a protein involved sulphur transfer in molybdopterin synthesis, is about the same length and shows limited sequence similarity to ThiS. Both have the conserved GG at the COOH end. no signal peptide. no TMHs. (83 aa)    
Predicted Functional Partners:
moaE
Molybdenum cofactor biosynthesis protein E; Molybdopterin converting factor subunit 2 (MPT synthase subunit 2) (Molybdopterin synthase subunit 2). Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group; High confidence in function and specificity.
  
 0.984
azo2929
Putative oxidoreductase. Homology to narC of C. perfringens of 27% (trembl|Q9WX91) InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs purD: phosphoribosylamine--glycine lig; Family membership.
 
  
  0.954
aorA
Probable aldehyde ferredoxin oxidoreductase. Homology to aorA of E. acidodaminophilum of 47% (trembl|Q93KC8) InterPro: Aldehyde ferredoxin oxidoreductase (IPR001203) Pfam: Aldehyde ferredoxin oxidoreductase, N-terminus; Aldeyhde ferredoxin oxidoreductase, damains 2&3 no TMHs no signal peptide; High confidence in function and specificity.
 
  
  0.922
azo2804
Adenylyltransferase, putative; Dinucleotide-utilizing enzyme involved in molybdopterin and/or thiamine biosynthesis Belongs to the hesA/moeB/thiF family, by similarity. TIGR00292: thiazole biosynthesis enzyme; High confidence in function and specificity.
   
 0.916
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 
 0.876
azo2931
Conserved hypothetical protein. Homology to gsu0911 of G. sulfurreducens of 38% (tremblnew|AAR34238). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs.
 
   
 0.859
azo3284
Conserved hypothetical protein. Homology to ne2229 of N. europaea of 38% (trembl|Q82SS7). no domains predicted. no signal peptide. no TMHs.
 
 
 0.837
thiG
Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
   
 
 0.828
azo2927
Conserved hypothetical protein. Homology to ebA5010 of Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebA5010(KEGG)). no domains predicted. no signal peptide. no TMHs.
       0.778
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
 
 0.737
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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