STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo2931Conserved hypothetical protein. Homology to gsu0911 of G. sulfurreducens of 38% (tremblnew|AAR34238). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs. (158 aa)    
Predicted Functional Partners:
aorA
Probable aldehyde ferredoxin oxidoreductase. Homology to aorA of E. acidodaminophilum of 47% (trembl|Q93KC8) InterPro: Aldehyde ferredoxin oxidoreductase (IPR001203) Pfam: Aldehyde ferredoxin oxidoreductase, N-terminus; Aldeyhde ferredoxin oxidoreductase, damains 2&3 no TMHs no signal peptide; High confidence in function and specificity.
 
 0.989
fdhC
Putative formate dehydrogenase gamma subunit. Homology to fdhC of W. succinogenes of 21% (TREMBL:P28180). Formate dehydrogenase is a membrane-bound complex, formed of at least three different subunits; probable heterotetramer of two FDHA, one FDHB and one FDHC. FdhC probably anchors the enzyme in the membrane and IS PROBABLY THE CYTOCHROME B556(FDO) COMPONENT. no good domains signal peptide 5 TMHs; Family membership.
 
 0.979
padB
Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padB of Azoarcus sp. EbN1 of 58% (gnl|keqq|eba:ebA5393(KEGG)). InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655). Pfam: Molypdopterin oxidoreductase; Molydopterin dinucleotide binding domain. no signal peptide. no TMHs; Function unclear.
 
 0.956
napA1
Nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
  
 0.941
napA2
Probable nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
  
 0.941
azo3661
Conserved hypothetical molybdopterin oxidoreductase. Homology to rsc2859 of R. solanacearum of 60% (trembl|Q8XVH2). Tigrfam: bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxidoreductases. Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain. Helixturnhelix motif. no signal sequenz. no TMHs; Conserved hypothetical protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.934
azo2929
Putative oxidoreductase. Homology to narC of C. perfringens of 27% (trembl|Q9WX91) InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs purD: phosphoribosylamine--glycine lig; Family membership.
 
 
 0.933
fdhA2
Probable formate dehydrogenase alpha subunit. Homology to fdha of W. succinogenes of 44% (pir|S18213) The formate dehydrogenase catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain singal peptide no TMHs; High confidence in function and specificity.
 
 
 0.897
azo0952
Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I, otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- [...]
   
    0.892
fdhA1
Probable formate dehydrogenase (NADP+), alpha subunit. Homology to fdh1A of M. extorquens of 60% (trembl|Q8KTI7). InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655); Respiratory-chain NADH dehydrogenase 75 kD subunit (IPR000283); Ferredoxin (IPR001041); 4Fe-4S ferredoxin, iron-sulfur binding domain (IPR001450) Pfam: 2Fe-2S iron-sulfur cluster binding domain; 4Fe-2S binding doami; Molybdopterin oxidase; Molybdopterin dinucloetide binding no signal peptide no TMHs; High confidence in function and specificity; Belongs to the prokaryotic molybdopterin-containing oxidoreductase [...]
 
 
 0.877
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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