STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
azo2950Multicopper oxidases are enzymes that possess three spectroscopically differentcopper centers. Similar to TREMBL:Q7X4G1 (71% identity); TREMBL:Q8U8U7 (71% identity); TREMBL:Q92ZC7 (70% identity). InterPro (IPR001117): Multicopper oxidase type 1. Pfam (PF00394): Multicopper oxidase. SignalP reporting signal peptide; Function unclear. (468 aa)    
Predicted Functional Partners:
azo2951
CopC: copper tolerance protein.CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm. 43% Cu-oxidase. InterPro:IPR008972; Cupredoxin. Signal pepetide:present. TMhelix:1; Function unclear.
 
 
 0.983
czcC
Putative outer membrane efflux protein involved in cobalt-zinc-cadmium resistance (Cation efflux system protein czcC). Homology to czcC of R. eutropha of 24%. czcC protein appears to modify the specificity of the system perhaps by acting on the czcB protein. When the czcC protein is added to czcA and czcB the efflux systems gained specificity for Cd(2+)and Co(2+) signal peptide no TMHs; Family membership.
 
   
 0.942
azo2952
Conserved hypothetical secreted protein. Homology to SMc02284 of S. meliloti of 38% (trembl|Q92S41(SRS)). Has PF07076:IPR009780;Protein of unknown function (DUF1344):This family consists of several short,hypothetical bacterial proteins of around 80 residues in length. Members of this family are found in Rhizobium,Agrobacterium and Brucella species. The function of this family is unknown. Signal peptide predicted. No TMHs; Conserved hypothetical protein.
 
   
 0.883
tatC
Probable Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
    
 
 0.841
tatB
Putative Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
   
 
 0.838
azo0187
Conserved hypothetical cytochrome c5. Homology to vc0168 of V. cloreae of 38% (tremble: Q9KVH8). This basic c-type monoheme cytochrome has an unusally low redox potential compaired with mitochaondrial cytochrome C. It is reactive with cytochrome c oxidase but not with reductase. Pfam: Cytrochrome C probable signal peptide no TMHs; Family membership.
    
 
 0.824
nosC
Conserved hypothetical cytochrome c5. Homology to nosC of A. eutrophus of 62% (trembl|Q7WX89). This basic c-type monoheme cytochrome has an unusually low redox potential compared with mitochondrial cytochrome c. It is reactive with cytochrome c oxidases but not with reductases. InterPro: Cytochrome c class I (IPR003088) Pfam: Cytorchrome C. signal peptide. no TMHs; Family membership.
    
 
 0.824
coxB
Conserved hypothetical cytochrome c oxidase,subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 0.780
azo2956
Similar to E.coli CopA: copper transporting P-type ATPase protein, involved in the uptake and metabolism of copper(EC 3.6.3.4).Involved in copper transport(By similarity). Putative cation transporting P-type ATPase (EC 3.6.3.-); High confidence in function and specificity.
 
  
 0.756
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
  0.721
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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