| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0835 | azo2555 | azo0835 | azo2555 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.741 |
| azo0835 | azo2953 | azo0835 | azo2953 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | Conserved hypothetical outer membrane efflux. Homology to ebA2169 Azoarcus sp. EbN1 of 68% (gnl|keqq|eba:ebA2169(KEGG)). Pfam: Outer membrane efflux protein. signal peptide. probable 1 TMH in signal peptide; Conserved hypothetical protein. | 0.900 |
| azo0835 | azo2955 | azo0835 | azo2955 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | Putative cation efflux system protein; Region start changed from 3242195 to 3242423 (-228 bases); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.706 |
| azo0835 | azo3135 | azo0835 | azo3135 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | Membrane fusion protein; HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q7W437 (52% identity); TREMBL:Q8EFT5 (32% identity). InterPro (IPR006143): Secretion protein HlyD. Pfam (PF00529): HlyD family secretion protein. TMHMM reporting one transmembrane helix. TC (8.A.1): The Membrane Fusion Protein (MFP) Family; Family membership. | 0.777 |
| azo0835 | azo3376 | azo0835 | azo3376 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | Membrane fusion protein; HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family. SignalP predicting signal peptide. TC (2.A.6.1): The Heavy Metal Efflux (HME) Family; Family membership. | 0.886 |
| azo0835 | cusB | azo0835 | azo2954 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | Cation efflux transmembrane protein; Putative membrane fusion protein silB precursor. COMPONENT OF THE SIL CATION-EFFLUX SYSTEM THAT CONFERS RESISTANCE TO SILVER. MAY BE PART OF A THREE-COMPONENT CATION/PROTON ANTIPORTER; High confidence in function and specificity. | 0.724 |
| azo0835 | hylD | azo0835 | azo0647 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | Putative HylD family secretion protein. Homology to hylD of E. coli of 24% (sprot|HLY4_ECOLI) Involved in the transport of hemolysin A. InterPro: HlyD family secretion protein; Gram-negative bacteril RTX secretion protein D Pfam: HylD family secretion protein no signal peptide no TMHs; Family membership. | 0.544 |
| azo0835 | macA | azo0835 | azo0612 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | Periplasmic component of efflux system; Macrolide-specific efflux protein macA precursor. Efflux transporter for macrolide antibiotics (By similarity). Membrane Fusion Protein (MFP) family; High confidence in function and specificity. | 0.871 |
| azo0835 | macB | azo0835 | azo0611 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | ATP-binding/permease fusion ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.924 |
| azo0835 | tolC | azo0835 | azo0850 | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | Putative outer membrane effluxe protein protein. Homology to tolC from E. coli of 33%. The OEP family (outer membreane effluxe protein) allow export of a variety of substrates in Gram negative bacteria. TolC is believed to be a membre af an ABC transporter system for protein secretion without cleavage of a signal sequence. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership. | 0.957 |
| azo2555 | azo0835 | azo2555 | azo0835 | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | 0.741 |
| azo2555 | azo2953 | azo2555 | azo2953 | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Conserved hypothetical outer membrane efflux. Homology to ebA2169 Azoarcus sp. EbN1 of 68% (gnl|keqq|eba:ebA2169(KEGG)). Pfam: Outer membrane efflux protein. signal peptide. probable 1 TMH in signal peptide; Conserved hypothetical protein. | 0.837 |
| azo2555 | azo2955 | azo2555 | azo2955 | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative cation efflux system protein; Region start changed from 3242195 to 3242423 (-228 bases); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.714 |
| azo2555 | azo3376 | azo2555 | azo3376 | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Membrane fusion protein; HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family. SignalP predicting signal peptide. TC (2.A.6.1): The Heavy Metal Efflux (HME) Family; Family membership. | 0.859 |
| azo2555 | hylD | azo2555 | azo0647 | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative HylD family secretion protein. Homology to hylD of E. coli of 24% (sprot|HLY4_ECOLI) Involved in the transport of hemolysin A. InterPro: HlyD family secretion protein; Gram-negative bacteril RTX secretion protein D Pfam: HylD family secretion protein no signal peptide no TMHs; Family membership. | 0.678 |
| azo2555 | macA | azo2555 | azo0612 | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Periplasmic component of efflux system; Macrolide-specific efflux protein macA precursor. Efflux transporter for macrolide antibiotics (By similarity). Membrane Fusion Protein (MFP) family; High confidence in function and specificity. | 0.860 |
| azo2555 | macB | azo2555 | azo0611 | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | ATP-binding/permease fusion ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.953 |
| azo2555 | tolC | azo2555 | azo0850 | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative outer membrane effluxe protein protein. Homology to tolC from E. coli of 33%. The OEP family (outer membreane effluxe protein) allow export of a variety of substrates in Gram negative bacteria. TolC is believed to be a membre af an ABC transporter system for protein secretion without cleavage of a signal sequence. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership. | 0.919 |
| azo2953 | azo0835 | azo2953 | azo0835 | Conserved hypothetical outer membrane efflux. Homology to ebA2169 Azoarcus sp. EbN1 of 68% (gnl|keqq|eba:ebA2169(KEGG)). Pfam: Outer membrane efflux protein. signal peptide. probable 1 TMH in signal peptide; Conserved hypothetical protein. | Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership. | 0.900 |
| azo2953 | azo2555 | azo2953 | azo2555 | Conserved hypothetical outer membrane efflux. Homology to ebA2169 Azoarcus sp. EbN1 of 68% (gnl|keqq|eba:ebA2169(KEGG)). Pfam: Outer membrane efflux protein. signal peptide. probable 1 TMH in signal peptide; Conserved hypothetical protein. | HlyD family secretion protein; Specificity unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.837 |
