Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo2960Conserved hypothetical transporter; 27% similarity to Hypothetical protein ycxA (ORF5)of Bacillus subtilis. 12 predicted transmembrane helices with signal peptide. 54% identity, 69% similarity to Pseudomonas putida membrane protein. InterPro: General substrate transporters 2A0111: Oxalate/Formate Antiporter; Function unclear. (405 aa)    
Predicted Functional Partners:
azo2961
Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Has Signal peptide.
       0.773
sigZ
Putative RNA polymerase sigma factor sigZ. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Similar to SWISSPROT: sprot|SIGZ_BACSU (23% Bacillus subtilis, RNA polymerase sigma factor SigZ) / sprot|RPSH_PSEAE (28% Pseudomonas aeruginosa, RNA polymerase sigma-h factor (sigma-30), AlgU or AlgT) InterPro: IPR000838 Sigma70_ECF. Pfam: PF07638 ECF sigma factor; High confidence in function and specificity.
  
  
 0.692
hylD
Putative HylD family secretion protein. Homology to hylD of E. coli of 24% (sprot|HLY4_ECOLI) Involved in the transport of hemolysin A. InterPro: HlyD family secretion protein; Gram-negative bacteril RTX secretion protein D Pfam: HylD family secretion protein no signal peptide no TMHs; Family membership.
  
 0.564
azo0835
Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership.
  
 0.564
metH
Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.529
azo3314
Conserved hypothetical secreted protein. Homology to PP2730 of P.putida of 48% (tremble:Q88JB9). No domains predicted. Signal peptide present. No TMH present; Conserved hypothetical protein.
  
  
  0.493
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
   
 
 0.490
azo1783
Conserved hypothetical membrane protein. Homology to ebA6946 of Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebA6946(KEGG)). Pfam: Pospholipase D, active site motife; DedA family. no signal peptide. 6 TMHs; Conserved hypothetical protein.
     
  0.488
pabB
Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear.
   
 
 0.472
azo2959
4-carboxymuconolactone decarboxylase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
       0.437
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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