STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2965Conserved hypothetical protein; Protein yhhW. SPROT:P46852: 51% identity, 69% similarity entry represents N-terminal domain of Pirin proteins from both eukaryotes and prokaryotes. The function of Pirin is unknown but the gene coding for this protein is known to be expressed in all tissues in the human body InterPro; IPR007113; Cupin_sup. InterPro; IPR003829; Pirin_N. Pfam; PF02678; Pirin; TIGR00292: thiazole biosynthesis enzyme Absence of transmembrane helices (TMHMM predicted); Function unclear. (228 aa)    
Predicted Functional Partners:
azo2966
Conserved hypothetical membrane protein. Homology to VPA0043 of Vibrio parahaemolyticus of 64% (trembl|Q87K55). Pfam: TQO small subunit DoxD. DoxD is a subunit of the terminal quinol oxidase present in the plasma membrane of Acidianus ambivalens, with calculated molecular mass of 20.4 kDa. Thiosulphate:quinone oxidoreductase (TQO) is one of the early steps in elemental sulphur oxidation. A novel TQO enzyme was purified from the thermo-acidophilic archaeon Acidianus ambivalens and shown to consist of a large subunit (DoxD) and a smaller subunit (DoxA). The DoxD- and DoxA-like two subuni [...]
  
  
 0.654
ygiD
Protocatechuate 4,5-dioxygenase; Putative cytoplasmic protein ygiD, 35% identity to TrEMBL;Q8ZLZ3. TrEMBL;Q8XBP3,Q83JK6. Has PF02900,Catalytic LigB subunit of aromatic ring-opening dioxygenase;IPR004183:The LigAB enzyme (a protocatechuate 4,5-dioxygenase), of Sphingomonas paucimobilis oxidizes protocatechuate (or 3,4-dihydroxybenzoic acid, PCA). The enzyme belongs to the class III extradiol-type catecholic dioxygenase family, which catalyzes the ring-opening reaction of protocatechuate and related compounds; Conserved hypothetical protein.
 
  
 0.608
chrA
Probable chromate transport protein.This protein reduces chromate accumulation and is essential for chromate resistance.Integral membrane protein.Induced by chromate. 27% Chromate_transpt. Pfam:PF02417; Chromate_transp; 2. TIGRFAMs:TIGR00937; 2A51; 1. TMHelix: 11. InterPro: Chromat transporter 2A51: Chromate Ion Transporter; High confidence in function and specificity.
       0.524
chrB
Probable Chromate resistance signal peptide protein, 49% Identity to TrEMBL; Q7NZK1, Q8XSC4. Has Signal Pepride.
       0.524
hupR
Transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
       0.424
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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