STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2966Conserved hypothetical membrane protein. Homology to VPA0043 of Vibrio parahaemolyticus of 64% (trembl|Q87K55). Pfam: TQO small subunit DoxD. DoxD is a subunit of the terminal quinol oxidase present in the plasma membrane of Acidianus ambivalens, with calculated molecular mass of 20.4 kDa. Thiosulphate:quinone oxidoreductase (TQO) is one of the early steps in elemental sulphur oxidation. A novel TQO enzyme was purified from the thermo-acidophilic archaeon Acidianus ambivalens and shown to consist of a large subunit (DoxD) and a smaller subunit (DoxA). The DoxD- and DoxA-like two subuni [...] (164 aa)    
Predicted Functional Partners:
azo2965
Conserved hypothetical protein; Protein yhhW. SPROT:P46852: 51% identity, 69% similarity entry represents N-terminal domain of Pirin proteins from both eukaryotes and prokaryotes. The function of Pirin is unknown but the gene coding for this protein is known to be expressed in all tissues in the human body InterPro; IPR007113; Cupin_sup. InterPro; IPR003829; Pirin_N. Pfam; PF02678; Pirin; TIGR00292: thiazole biosynthesis enzyme Absence of transmembrane helices (TMHMM predicted); Function unclear.
  
  
 0.654
azo2855
Conserved hypothetical protein. Homology to PP2399 of P.putida of 36% (trembl:Q88K92). No domains predicted. No TMHs. No signal peptide.
 
  
 0.645
azo2854
Conserved hypothetical protein. Homology to PA3283 of P.aeruginosa of 54% (trembl:Q9HYW0). Has PF05114,Protein of unknown function (DUF692);IPR007801:This family consists of several uncharacterised bacterial proteins. No signal peptide or TMH present.
  
  
 0.595
hupR
Transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
       0.536
wrbA1
Probable trp repressor binding protein (flavodoxin); SPROT:Q92PU3: 71% identity; 82% similarity Flavoprotein wrbA1. cofactor:binds 1 fmn per monomer (by similarity). similarity:belongs to the wrba family; contains 1 flavodoxin-like domain. InterPro:IPR008254; Flav_nitox_synth. IPR001226; Flavodoxin. Pfam: PF00258; flavodoxin; 1. Absence of signal peptide (Signal P predicted) and transmembrane helices (TMHMM predicted) met_pdase_I: methionine aminopeptidase t; High confidence in function and specificity.
 
    0.464
msrP
Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...]
  
 
 0.458
chrA
Probable chromate transport protein.This protein reduces chromate accumulation and is essential for chromate resistance.Integral membrane protein.Induced by chromate. 27% Chromate_transpt. Pfam:PF02417; Chromate_transp; 2. TIGRFAMs:TIGR00937; 2A51; 1. TMHelix: 11. InterPro: Chromat transporter 2A51: Chromate Ion Transporter; High confidence in function and specificity.
       0.450
azo2669
Conserved hypothetical cytochrome c family protein. Homology to bra0353 of B. suis of 50% (trembl|Q8FWU2). InterPro: Cytochrome c class I (IPR003088). Pfam: cytochrome c. signal peptide. no TMHS; Function unclear.
    
  0.426
sseA
SseA: putative thiosulfate sulfurtransferase (rhodanese-like protein) [EC:2.8.1.1]. This protein transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity (130-fold lower). Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity. Probable 3-mercaptopyruvate sulfurtransferase (EC 2.8.1.2) (Rhodanese- like protein) (MST). InterPro: Rhodanese/cdc25 fold; High confidence in function and specificity.
  
 
 0.425
azo2594
Conserved hypothetical membrane protein. Homology to CV2219 of Chromobacterium violaceum of 36% (trembl|Q7NVX2(SRS)). no domains predicted. no signal peptide. 1 TMHs; Conserved hypothetical protein.
  
  
  0.417
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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