STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exaA2Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 73% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present; High confidence in function and specificity. (625 aa)    
Predicted Functional Partners:
exaB2
Putative cytochrome c550. Homology to exaB of P. aeruginosa of 37% (trembl|Q9Z4P8). Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation. InterPro: Cytochrome c class I (IPR003088) Pfam: cytochrome c signal peptide no TMHs; Function unclear.
 
 
 0.925
exaB1
Probable cytochrome c550. Homology to exaB of P. aeruginosa of 57% (trembl|Q9Z4P8) Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation system InterPro: Cytochrome c class I ((IPR003088) Pfam: Cytochrome c signal peptide no TMHs; High confidence in function and specificity.
 
 
 0.859
azo2935
Conserved hypothetical protein TMHMM2 reporting the presence of 1 TMH's. No Signal peptide present. Has 2 WD40 repeats;SMART;SM00320, Beta-transducin (G-beta) is one of the three subunits (alpha, beta, and gamma) of the guanine nucleotide-binding proteins (G proteins) which act as intermediaries in the transduction of signals generated by transmembrane receptors (see IPR001632). The alpha subunit binds to and hydrolyzes GTP; the functions of the beta and gamma subunits are less clear but they seem to be required for the replacement of GDP by GTP as well as for membrane anchoring and re [...]
 
 
 0.821
azo2934
Conserved hypothetical amino acid-binding protein. Homology to pp2676 of P. putida of 34% (trembl|Q88JH3). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR amino acids. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638); solute binding protein /glutamate receptor (IPR001311). Pfam: Bacterial extracellular solute-binding protein. singal peptide. no TMHs; Specificity unclear.
 
  
 0.812
azo2976
Conserved hypothetical secreted protein. Homology to PP2677 of P. putida of 35% (trembl|Q88JH2(SRS)). No domains predicted. Signal peptide present. No TMH detected; Conserved hypothetical protein.
 
  
  0.809
pqqB
Probable coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
 
  
 0.793
pqqC
Coenzyme PQQ synthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
 
  
 0.788
pqqE
Pyrroloquinoline quinone synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
 
  
 0.737
cphA
Putative beta lactamase precursor; Conserved Hypothetical protein (pir:H95862; 47% identity), putative hydrolase (TREMBL: Q88JH1; 54% identity, 66% similarity) putative cyclase (TREMBL: Q93IZ0) putative alkylsufatase/betalactamase (rba:RB11502) Metallo beta lactamase superfamily (Pfam) Signal P; TMHMM reporting transmembrane helices S18: ribosomal protein S18; High confidence in function and specificity.
 
     0.726
exaA5
Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 32% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. SWISSPROT:DHET_GLUOX:O05542.30%; High confidence in function and specificity.
  
  
 
0.719
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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