Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cphAPutative beta lactamase precursor; Conserved Hypothetical protein (pir:H95862; 47% identity), putative hydrolase (TREMBL: Q88JH1; 54% identity, 66% similarity) putative cyclase (TREMBL: Q93IZ0) putative alkylsufatase/betalactamase (rba:RB11502) Metallo beta lactamase superfamily (Pfam) Signal P; TMHMM reporting transmembrane helices S18: ribosomal protein S18; High confidence in function and specificity. (330 aa)    
Predicted Functional Partners:
azo2976
Conserved hypothetical secreted protein. Homology to PP2677 of P. putida of 35% (trembl|Q88JH2(SRS)). No domains predicted. Signal peptide present. No TMH detected; Conserved hypothetical protein.
 
     0.950
exaA3
Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 53% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. TMhelix:1; High confidence in function and specificity.
 
   
 0.823
azo2978
Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.
 
     0.816
exaB1
Probable cytochrome c550. Homology to exaB of P. aeruginosa of 57% (trembl|Q9Z4P8) Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation system InterPro: Cytochrome c class I ((IPR003088) Pfam: Cytochrome c signal peptide no TMHs; High confidence in function and specificity.
 
   
 0.762
exaB2
Putative cytochrome c550. Homology to exaB of P. aeruginosa of 37% (trembl|Q9Z4P8). Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation. InterPro: Cytochrome c class I (IPR003088) Pfam: cytochrome c signal peptide no TMHs; Function unclear.
 
   
 0.759
elmS
Putative two-component sensor histidine kinase,; Specificity unclear.
 
     0.745
azo2934
Conserved hypothetical amino acid-binding protein. Homology to pp2676 of P. putida of 34% (trembl|Q88JH3). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR amino acids. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638); solute binding protein /glutamate receptor (IPR001311). Pfam: Bacterial extracellular solute-binding protein. singal peptide. no TMHs; Specificity unclear.
  
     0.731
exaA2
Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 73% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present; High confidence in function and specificity.
 
   
 0.728
azo3948
Putative DNA-directed polymerase III; Excinuclease cho (EC 3.1.25.-) (Endonuclease cho) (UvrC homolog protein). Incises the DNA at the 3 side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than uvrC. Not able to incise the 5 site of a lesion. When a lesion remains because uvrC is not able to induce the 3 incision cho incises the DNA. Then uvrC makes the 5 incision. The combined action of cho and uvrC broadens the substrate range of nucleotide excision repair (By similarity); Specificity unclear.
    
 0.628
azo1211
Conserved hypothetical protein. Homology bll7767 of B. japonicum of 30% (trembl|Q89CN0) Pfam: WD domain, G-beta repeat no signal peptide no TMHs.
    
  0.602
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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