azo2978 protein (Azoarcus sp. BH72) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

azo2978

Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity. (804 aa)

Predicted Functional Partners:

azo2976

0.840

elmS

0.835

cphA

0.816

exaA3

0.689

azo0984

0.659

gumB

0.654

azo1761

0.631

wza

0.631

azo0235

0.608

tolA

0.608

Your Current Organism:

Azoarcus sp. BH72

NCBI taxonomy Id: 62928
Other names: A. sp. BH72

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
azo0235	azo2978	azo0235	azo2978	Conserved hypothetical membrane protein. Homology to an orf of Rubrivivax gelatinosus of 55% (gi\|47575633\|ref\|ZP_00245668.1\|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein.	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	0.608
azo0984	azo1761	azo0984	azo1761	Conserved hypothetical secreted protein. Homology to NE1634 of Nitrosomonas europaea of 34% (trembl\|Q82U71(SRS)) No domains predicted. No TMHs Signal peptide present; Conserved hypothetical protein.	Hypothetical protein, Shares 45% similarity with hypothetical protein [Chromobacterium violaceum]TrEMBL Q7NY28. Signal Peptide present. No TMH's reported. Has pfam05359, DUF748, Domain of Unknown Function (DUF748); Specificity unclear.	0.619
azo0984	azo2978	azo0984	azo2978	Conserved hypothetical secreted protein. Homology to NE1634 of Nitrosomonas europaea of 34% (trembl\|Q82U71(SRS)) No domains predicted. No TMHs Signal peptide present; Conserved hypothetical protein.	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	0.659
azo0984	wza	azo0984	azo3283	Conserved hypothetical secreted protein. Homology to NE1634 of Nitrosomonas europaea of 34% (trembl\|Q82U71(SRS)) No domains predicted. No TMHs Signal peptide present; Conserved hypothetical protein.	Conserved hypothetical polysaccharid export protein. Homology to wza of Azoarcus sp. EbN1 of 80%. Pfam: Polysaccharide biosynthesis/export protein. This is a family of periplasmic proteins involved in polysaccharide biosynthesis and/or export. No TMHs. Signal peptide present., ; Family membership.	0.763
azo1761	azo0984	azo1761	azo0984	Hypothetical protein, Shares 45% similarity with hypothetical protein [Chromobacterium violaceum]TrEMBL Q7NY28. Signal Peptide present. No TMH's reported. Has pfam05359, DUF748, Domain of Unknown Function (DUF748); Specificity unclear.	Conserved hypothetical secreted protein. Homology to NE1634 of Nitrosomonas europaea of 34% (trembl\|Q82U71(SRS)) No domains predicted. No TMHs Signal peptide present; Conserved hypothetical protein.	0.619
azo1761	azo2978	azo1761	azo2978	Hypothetical protein, Shares 45% similarity with hypothetical protein [Chromobacterium violaceum]TrEMBL Q7NY28. Signal Peptide present. No TMH's reported. Has pfam05359, DUF748, Domain of Unknown Function (DUF748); Specificity unclear.	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	0.631
azo1761	gumB	azo1761	azo2242	Hypothetical protein, Shares 45% similarity with hypothetical protein [Chromobacterium violaceum]TrEMBL Q7NY28. Signal Peptide present. No TMH's reported. Has pfam05359, DUF748, Domain of Unknown Function (DUF748); Specificity unclear.	Putative capsule polysaccharide export protein precursor.May be involved in polysaccharide polymerization or transport. 36% Poly_export. Pfam:PF02563; Poly_export; 1. Signal peptide: present; Family membership.	0.692
azo1761	wza	azo1761	azo3283	Hypothetical protein, Shares 45% similarity with hypothetical protein [Chromobacterium violaceum]TrEMBL Q7NY28. Signal Peptide present. No TMH's reported. Has pfam05359, DUF748, Domain of Unknown Function (DUF748); Specificity unclear.	Conserved hypothetical polysaccharid export protein. Homology to wza of Azoarcus sp. EbN1 of 80%. Pfam: Polysaccharide biosynthesis/export protein. This is a family of periplasmic proteins involved in polysaccharide biosynthesis and/or export. No TMHs. Signal peptide present., ; Family membership.	0.619
azo2976	azo2978	azo2976	azo2978	Conserved hypothetical secreted protein. Homology to PP2677 of P. putida of 35% (trembl\|Q88JH2(SRS)). No domains predicted. Signal peptide present. No TMH detected; Conserved hypothetical protein.	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	0.840
azo2976	cphA	azo2976	azo2977	Conserved hypothetical secreted protein. Homology to PP2677 of P. putida of 35% (trembl\|Q88JH2(SRS)). No domains predicted. Signal peptide present. No TMH detected; Conserved hypothetical protein.	Putative beta lactamase precursor; Conserved Hypothetical protein (pir:H95862; 47% identity), putative hydrolase (TREMBL: Q88JH1; 54% identity, 66% similarity) putative cyclase (TREMBL: Q93IZ0) putative alkylsufatase/betalactamase (rba:RB11502) Metallo beta lactamase superfamily (Pfam) Signal P; TMHMM reporting transmembrane helices S18: ribosomal protein S18; High confidence in function and specificity.	0.950
azo2976	elmS	azo2976	azo2979	Conserved hypothetical secreted protein. Homology to PP2677 of P. putida of 35% (trembl\|Q88JH2(SRS)). No domains predicted. Signal peptide present. No TMH detected; Conserved hypothetical protein.	Putative two-component sensor histidine kinase,; Specificity unclear.	0.775
azo2976	exaA3	azo2976	azo2975	Conserved hypothetical secreted protein. Homology to PP2677 of P. putida of 35% (trembl\|Q88JH2(SRS)). No domains predicted. Signal peptide present. No TMH detected; Conserved hypothetical protein.	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 53% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. TMhelix:1; High confidence in function and specificity.	0.849
azo2978	azo0235	azo2978	azo0235	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	Conserved hypothetical membrane protein. Homology to an orf of Rubrivivax gelatinosus of 55% (gi\|47575633\|ref\|ZP_00245668.1\|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein.	0.608
azo2978	azo0984	azo2978	azo0984	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	Conserved hypothetical secreted protein. Homology to NE1634 of Nitrosomonas europaea of 34% (trembl\|Q82U71(SRS)) No domains predicted. No TMHs Signal peptide present; Conserved hypothetical protein.	0.659
azo2978	azo1761	azo2978	azo1761	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	Hypothetical protein, Shares 45% similarity with hypothetical protein [Chromobacterium violaceum]TrEMBL Q7NY28. Signal Peptide present. No TMH's reported. Has pfam05359, DUF748, Domain of Unknown Function (DUF748); Specificity unclear.	0.631
azo2978	azo2976	azo2978	azo2976	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	Conserved hypothetical secreted protein. Homology to PP2677 of P. putida of 35% (trembl\|Q88JH2(SRS)). No domains predicted. Signal peptide present. No TMH detected; Conserved hypothetical protein.	0.840
azo2978	cphA	azo2978	azo2977	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	Putative beta lactamase precursor; Conserved Hypothetical protein (pir:H95862; 47% identity), putative hydrolase (TREMBL: Q88JH1; 54% identity, 66% similarity) putative cyclase (TREMBL: Q93IZ0) putative alkylsufatase/betalactamase (rba:RB11502) Metallo beta lactamase superfamily (Pfam) Signal P; TMHMM reporting transmembrane helices S18: ribosomal protein S18; High confidence in function and specificity.	0.816
azo2978	elmS	azo2978	azo2979	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	Putative two-component sensor histidine kinase,; Specificity unclear.	0.835
azo2978	exaA3	azo2978	azo2975	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 53% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. TMhelix:1; High confidence in function and specificity.	0.689
azo2978	gumB	azo2978	azo2242	Putative TonB-dependent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.	Putative capsule polysaccharide export protein precursor.May be involved in polysaccharide polymerization or transport. 36% Poly_export. Pfam:PF02563; Poly_export; 1. Signal peptide: present; Family membership.	0.654

page 1 of 3

Server load: low (10%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About