azo2986 protein (Azoarcus sp. BH72) - STRING interaction network

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Score

azo2986

Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear. (216 aa)

Predicted Functional Partners:

azo2987

0.808

gcvP

0.754

azo0628

0.547

ribAB

0.530

glyA

0.513

rmlC

0.450

chrR

0.407

Your Current Organism:

Azoarcus sp. BH72

NCBI taxonomy Id: 62928
Other names: A. sp. BH72

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
azo0628	azo2986	azo0628	azo2986	Putative adenylate/guanylate cyclase,; Conserved hypothetical protein.	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	0.547
azo0628	ribAB	azo0628	azo0319	Putative adenylate/guanylate cyclase,; Conserved hypothetical protein.	GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.891
azo2986	azo0628	azo2986	azo0628	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	Putative adenylate/guanylate cyclase,; Conserved hypothetical protein.	0.547
azo2986	azo2987	azo2986	azo2987	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	Putative Dihydrofolate reductase; Function unclear.	0.808
azo2986	chrR	azo2986	azo2988	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	Probable chromate reductase. Homology to chrR of E. coli of 49% (tremblnew\|AAK62985). Reduction of chromate (Cr(VI)) to Cr(III).no no signal peptide no TMHs; High confidence in function and specificity.	0.407
azo2986	gcvP	azo2986	azo1285	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.754
azo2986	glyA	azo2986	azo2801	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.513
azo2986	ribAB	azo2986	azo0319	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.530
azo2986	rmlC	azo2986	azo1874	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	0.450
azo2987	azo2986	azo2987	azo2986	Putative Dihydrofolate reductase; Function unclear.	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	0.808
azo2987	chrR	azo2987	azo2988	Putative Dihydrofolate reductase; Function unclear.	Probable chromate reductase. Homology to chrR of E. coli of 49% (tremblnew\|AAK62985). Reduction of chromate (Cr(VI)) to Cr(III).no no signal peptide no TMHs; High confidence in function and specificity.	0.407
azo2987	glyA	azo2987	azo2801	Putative Dihydrofolate reductase; Function unclear.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.469
chrR	azo2986	azo2988	azo2986	Probable chromate reductase. Homology to chrR of E. coli of 49% (tremblnew\|AAK62985). Reduction of chromate (Cr(VI)) to Cr(III).no no signal peptide no TMHs; High confidence in function and specificity.	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	0.407
chrR	azo2987	azo2988	azo2987	Probable chromate reductase. Homology to chrR of E. coli of 49% (tremblnew\|AAK62985). Reduction of chromate (Cr(VI)) to Cr(III).no no signal peptide no TMHs; High confidence in function and specificity.	Putative Dihydrofolate reductase; Function unclear.	0.407
gcvP	azo2986	azo1285	azo2986	Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	0.754
gcvP	glyA	azo1285	azo2801	Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.995
gcvP	ribAB	azo1285	azo0319	Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.466
glyA	azo2986	azo2801	azo2986	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Putative methyltransferase; Similar to TREMBL:Q82SQ0 (50% identity, 67% similarity); Function unclear.	0.513
glyA	azo2987	azo2801	azo2987	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Putative Dihydrofolate reductase; Function unclear.	0.469
glyA	gcvP	azo2801	azo1285	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.995